Biomarkers – News and Features
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Using Handgrip Strength To Predict Age-Related Disease and Disability
A groundbreaking study has created the world’s largest and most geographically comprehensive international norms for handgrip strength, enabling global peer comparison, health screening and surveillance across the adult lifespan.
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Epigenetic Markers Could Help Detect Preeclampsia Early
Research has identified DNA methylation markers associated with preeclampsia, a serious pregnancy complication. By analyzing cheek cells, scientists found 389 unique methylation sites linked to the condition.
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Computational Pipeline Offers Insights Into Alzheimer's and Potential Drug Targets
A novel computational pipeline has been designed to identify protein biomarkers associated with complex diseases, including Alzheimer’s disease.
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Using Optical Fibers To Prevent Brain Injury Complications
Researchers have developed an optical fiber sensing system that could help medical professionals monitor patients for complications after a traumatic brain injury.
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Predicting the Effectiveness of Spinal Cord Stimulation
Spinal cord stimulation is often a last resort for those with intractable chronic pain. A new 10-minute brain scan gives doctors a much-needed biomarker to discuss with patients considering spinal cord stimulation.
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How Plant-Based Diets Can Help Prevent GI Cancers
Flinders University study highlights the protective effects of plant-based diets against gastrointestinal cancers. Diets rich in fiber, fruits, vegetables, and whole grains were linked to lower cancer risks, while processed and sugary foods increase.
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Mechanisms That Make Ewing Sarcoma More Aggressive Discovered
A study from Spain’s CNIO identifies genetic alterations linked to STAG2 loss, driving aggressiveness in Ewing sarcoma. These changes increase metastasis and impact immune response, offering new prognostic markers and therapeutic targets.
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Protein Accumulation Linked to Neurological Symptoms of Long COVID
Researchers have identified that the SARS-CoV-2 spike protein accumulates in the brain's protective layers, potentially explaining the neurological symptoms of long COVID.
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Protein Mobility May Be a Key Driver of Decreased Cellular Function in Chronic Disease
A study identifies "proteolethargy," reduced protein mobility caused by oxidative stress, as a unifying mechanism in chronic diseases. The findings suggest that impaired protein movement disrupts cellular functions.
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Long-Term Hormone Therapy Reveals Cardiovascular Risks in Trans Men
A study highlights significant body composition changes and increased cardiovascular risks in transgender men on testosterone therapy. Over six years, muscle volume rose by 21%, abdominal fat by 70%, and LDL cholesterol increased.
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