CRISPR and Genome Editing – News and Features

News
Cancer Immunotherapy Enhanced by Rewiring T-Cell Metabolism
Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way to enhance the immune system's ability to fight cancer by reprogramming T-cell metabolism.

Article
Bacterial Conjugation – Conjugation Biology Explained
Conjugation is a form of horizontal gene transfer that allows the exchange of genetic material between two organisms or cells. In this article, we discuss the mechanism of conjugation and how scientists use it to manipulate bacterial genomes.

News
Automation Accelerates Bioactive Natural Product Discovery
Natural products have become a mainstay in modern society and are used for numerous applications such as medicine and pesticides. Researchers have now developed a new method to accelerate bioactive natural product discovery.

Industry Insight
AI’s Next Horizon: Cell and Gene Therapy Manufacturing
Dalip Sethi provides valuable insights on how AI is currently being carefully and critically considered within the cell and gene therapy industry, with regard to data and technological preparedness.

News
CRISPR Therapy Eliminates 50% of Head and Neck Tumors
Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study highlights CRISPR’s potential for cancer treatment.

News
How Regular Blood Donors Shape Their Stem Cell Genetics
Researchers found that frequent blood donation may favor genetic adaptations in blood stem cells, promoting healthy regeneration. While mutations in leukemia-associated genes were present, they differed from preleukemic variants.

Industry Insight
Overcoming CAR T-Cell Therapy Limitations
In an interview with Arthur Stril, chief business officer and interim CFO at Cellectis, we explore how gene editing and innovative manufacturing strategies are overcoming the key limitations of autologous CAR T-cell therapy.

Article
Inducible Degrons Help Researchers Catalog Gene Function
Technology Networks caught up with Professor Mazhar Adli to learn more about his research on the characterization of essential human genes and the benefits of using inducible degrons to study gene function.

News
The Brain’s Motor Cortex Is More Modular Than We Thought
A study reveals that motor control in the brain is modular and adaptable. Using optogenetics and imaging in mice, researchers identified horizontal networks that reorganize as new skills are learned.

News
Strains of Aspergillus fumigatus Five Times More Likely To Acquire Resistance to Antifungals
Researchers have identified strains of one of the world's most dangerous pathogens that are five times more likely to acquire antifungal resistance.
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