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CRISPR and Genome Editing – News and Features

Multi-channel pipette, pipetting into wells
News

Genetic Tweak Boosts Drug-Making Cells by Blocking Toxic Byproducts

Researchers have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.
A hand pinching a capsule.
News

Self-Assembling Molecules Developed With Applications in Targeted Drug Discovery

A collaborative team has developed a new method to program molecular self-assembly predictably. Researchers created versatile materials like "Malteser molecules," which could serve as highly specific sensors or drug delivery agents.
Chromosomes from cancer cells with DNA stained blue, telomeres stained green, and centromeres stained pink.
News

How Cancer Cells Die Differently After Radiotherapy

A study reveals that the way cancer cells die after radiotherapy depends on DNA repair methods. By blocking specific repair pathways, scientists can prompt immune responses against cancer cells.
Cells.
News

Study Reveals How Two Common CAR T Cells Kill Cancer

A study explores the molecular dynamics of CD28.ζ-CAR and 4-1BB.ζ-CAR T cells at the immune synapse, where CAR T cells bind to cancer cells. CD28.ζ-CAR T cells act like sprinters, killing cancer cells quickly but briefly
Tomatoes ripening on a branch.
News

Cracking the Code of Fruit Ripening

A study uncovers how H2O2-induced redox modification regulates the RNA demethylase SlALKBH2. This modification stabilizes SlALKBH2 and accelerates tomato ripening without altering its m6A demethylase activity.
Sun shines through a lemon tree.
News

Genetically-Modified Citrus Tree Could Be Immune to Psyllid Pests

Scientists at the University of Florida are testing a new type of citrus tree that can fight off the tiny insects responsible for citrus greening.
An artistic representation of T cells
Article

Understanding T Cells: T Cell Types, the T Cell Receptor and T Cell Activation, Differentiation and Functions

The adaptive immune system is highly complex and specific. In this article we focus on T cells, and discuss their development, their different functions, and what happens when they don't function correctly.
Two researchers in a lab.
News

New Gene Editing Tool Tackles Multiple Diseases Simultaneously

Penn researchers introduce mvGPT, a gene editing tool that edits DNA, activates genes and represses gene expression simultaneously. Successfully tested on cells with Wilson’s disease, mvGPT addresses multiple conditions with high precision.
A woman performing sit-ups on a gym mat.
News

Brown Fat Shows Potential to Boost Exercise and Healthy Aging

Rutgers researchers highlight the role of brown adipose tissue (BAT) in boosting endurance and promoting healthy aging. BAT improves blood circulation, reduces cellular stress and enhances metabolism
Double helix structure of DNA.
News

CRISPR Therapy Shows Promise for Muscular Dystrophy in Mice

ECRC researchers developed a CRISPR-based gene therapy targeting dysferlin mutations in muscular dystrophy. By editing and transplanting corrected muscle stem cells, they restored protein function and regrew muscle in preclinical models.
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