CRISPR and Genome Editing – News and Features

Using cryo-electron microscopy, researchers uncovered how sodium ions drive bacterial flagellar motors, revealing key molecular structures. Their findings could aid in developing antibacterial treatments.

Scientists at Children’s Medical Research Institute (CMRI) have solved a big mystery in cancer research – why cells die in different ways following radiotherapy.

UConn researchers have identified a small molecule that disrupts PRRSV, a virus costing the swine industry billions annually. The molecule blocks the NendoU protein, reducing viral replication 1,000-fold.

By activating a master epigenetic switch using CRISPR, naturally suppressed genes can be turned on, offering hope for Prader-Willi syndrome.

Researchers have developed a new avenue to reprogram compromised immune cells to act against tumors. The findings highlight a potential path forward for treating late-stage tumors that have become resistant to current therapies.

Synthetic biologists from Yale were recode the genetic code of an organism, a novel genomically recoded organism (GRO) with one-stop codon, using a cellular platform that they developed enabling the production of new classes of synthetic

A new study reveals that modifying the CUL5 gene enhances CAR-T cell therapy for leukemia and lymphoma. This improves cell longevity and tumor-fighting power, reducing cancer relapse.

Racial disparities in mortality are increasing. This article explores how the production of DNA-edited ethnically diverse stem cell lines for disease research could improve global health equity.

Dr. John Lee, global head of cell and gene therapy at SK pharmteco discusses the current challenges in plasmid manufacturing and how SK pharmteco’s Precision Plasmids™ technology can help overcome plasmid production bottlenecks.

A new study reveals that tau protein affects memory, while beta-amyloid disrupts emotions in Alzheimer’s disease. Using a novel mouse model, researchers found that both proteins interact to worsen brain inflammation.