Multiomics – Multimedia

There is more to DNA than A, C, G and T, epigenetics plays a causal role in cell fate, aging and disease development. Genetic and methylation data together on the same read allow us to get a more complete picture of genome biology. Constrained to measuring four states of information, existing NGS- based technologies sacrifice genetic for methylation calling.

Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype. However, a standard blood draw yields an average of only 10 ng of cfDNA, of which DNA derived from the tumor is a small minority.

Download this listicle to discover recent examples of how single-cell analysis methods are driving forward research into cancer, aging, and drug discovery and development.

Need a routine analytical technique that can provide protein expression profiling and targeted drug imaging? MALDI Imaging is used to determine the spatial distribution of molecules in a tissue section, for more complete multiomic information.

In this episode we discuss how the combination of both genetic and epigenetic information within a single DNA sample can provide key insights on the dynamic interactions that are occurring, offering significant advantages in many research areas.

Speaking at ‘Advances in Proteomics & Metabolomics’ 2022, Erik Johnson from Emory University, presented their talk on proteomics in Alzheimer’s disease.

Single-cell RNA sequencing produces a substantial amount of complex data that can be a burden if you don’t have time to become an expert in bioinformatics.

Inherited metabolic disorders (IMDs) are a vast and complex group of rare genetic diseases presenting throughout a patient’s life span.

Extracting biological insights from spatial data is vital to advancing science, however, the analysis of spatial multiomics data is only possible with a robust and scalable informatics solution.

Download this listicle to learn more about high-throughput screening, mass spectrometry-based technologies, multiomics research and high-throughput drug screening.