Pharmacovigilance – Multimedia
App Note / Case Study
Optimizing Detection of Leachables To Ensure Drug Safety
This application note explores the use of gas chromatography and mass spectrometry techniques to identify and quantify volatile compounds in rubber gasket extracts.
App Note / Case Study
Streamlined Detection and Characterization of Mitochondrial Toxicants
This app note highlights an assay that enables streamlined, sensitive detection and characterization of mitochondrial toxicants.
App Note / Case Study
Achieve Sensitive Quantitation of GLP Analogs in Biological Matrices
Glucagon-like peptide-1 (GLP-1) analogs regulate systemic homeostasis, making them effective in the treatment of type 2 diabetes. However, their low bioavailability limits their detection and quantitation in biological matrices, causing challenges in drug development.
eBook
An Introduction to Organ-on-a-Chip Technology
This eBook provides an introduction to Organ-on-a-Chip technology and highlights the latest solutions available to support drug discovery.
App Note / Case Study
Optimizing Organoid Culture Conditions
This application note outlines the importance of reagent consistency in organoid tissue culture.
Video
The Return of Thalidomide
Research is finding that thalidomide is still worth using, despite the risks. So what makes this drug that causes life-altering fetal abnormalities such a good thing?
Infographic
Tackling Cardiotoxicity During Drug Development
Did you know that the adverse effect of drugs on cardiac tissue – known as cardiotoxicity – is one of the principal reasons that therapeutics are withdrawn from the market?
Listicle
Current Trends and Future Prospects in Immuno-Oncology
Immunotherapy aims to leverage the power of the immune system in the fight against cancer. It offers a more effective and less destructive approach than many traditional treatments.
App Note / Case Study
Highly Sensitive Mass Spectrometry Methods for Quantifying PROTACs
Protein-targeting chimeras (PROTACs) have gained significant attention recently due to their high potency in nanomolar drug concentrations and target selectivity. However, low test concentrations in complex matrices present analytical challenges.
Video
Next-Generation STING Agonists for Immunotherapy Against Advanced Cancer
Speaking at The Landscape of Cancer Research 2022 online symposium, James Moon from the University of Michigan delivered his talk on next-generation STING agonists for immunotherapy against advanced cancer.
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