Therapeutic Delivery – News and Features

Oregon State researchers discovered that exposing a copper-based MOF to ammonia gas doubles its CO2 adsorption ability. This method enhances carbon capture efficiency without increasing regeneration energy.

University of Waterloo researchers developed 3D-printed hydrogel-loaded contact lenses that deliver medication continuously while worn. The silicone-based hydrogel is durable, flexible and can encapsulate drugs like amoxicillin.

Researchers have developed programmable DNA nanostructures using DNA origami. These customizable nanobots have vast applications, from targeted drug delivery and adaptive materials to energy-efficient optical systems.

A tiny, four-fingered “hand” folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them.

Researchers developed a gene therapy to enhance placental function by delivering IGF-1 DNA using nanoparticles. Tested in rhesus macaques, the therapy improved placental health without adverse effects.

A nasal spray drug can counteract the cognitive decline and brain damage typical of Alzheimer's disease in animal models.

A Mount Sinai team has developed a blood-brain barrier-crossing conjugate (BCC) platform, enabling therapeutic molecules to target the brain. The system effectively silenced disease-related genes like Sod1 in ALS and Mapt in Alzheimer’s.

This article explores the difficulties faced in attempting to treat HIV, an innovative prevention strategy and the possibility of a cure.

Short-term menopausal hormone therapy (mHT) does not have long-term cognitive effects when given to women in early postmenopause, according to new research from Mayo Clinic scientists.

Researchers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies.