Therapeutic Delivery – News and Features

Researchers developed a gene therapy to enhance placental function by delivering IGF-1 DNA using nanoparticles. Tested in rhesus macaques, the therapy improved placental health without adverse effects.

A nasal spray drug can counteract the cognitive decline and brain damage typical of Alzheimer's disease in animal models.

A Mount Sinai team has developed a blood-brain barrier-crossing conjugate (BCC) platform, enabling therapeutic molecules to target the brain. The system effectively silenced disease-related genes like Sod1 in ALS and Mapt in Alzheimer’s.

This article explores the difficulties faced in attempting to treat HIV, an innovative prevention strategy and the possibility of a cure.

Short-term menopausal hormone therapy (mHT) does not have long-term cognitive effects when given to women in early postmenopause, according to new research from Mayo Clinic scientists.

Researchers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies.

Nanoparticles coated with polymers made with natural sugars could reduce the immune response to cancer treatment, making it more effective.

RNA therapeutics promise rapid, personalized and flexible treatments against multiple diseases. In this article, we will explore whether RNA therapeutics can realize their full potential.

Machine learning and supercomputer simulations have been used to investigate how tiny gold nanoparticles bind to blood proteins.

A FAMU-FSU engineering team discovered that adding sodium chloride to polyzwitterions enhances adhesive strength and flexibility. The study compared bottlebrush and linear polymers, finding that electrostatic interactions drive improved bonding.