Life According to Orbitrap - Is Bigger Better?

Interview with Dr. Hannes Röst, Principal Investigator at the University of Toronto, describes how his lab is using diaPASEF to monitor the human proteome throughout a person's lifetime, and how machine learning could be used to analyze the data.

Scientists from the University of Bristol, CNRS and Imophoron Ltd worked with the computer technology giant Oracle to develop a new kind of vaccine that needs no refrigeration. They used synthetic biology, cryo-electron microscopy and high-performance cloud computing to produce a candidate vaccine against the mosquito-borne chikungunya virus. Their findings could revolutionise the way vaccines are designed, developed and stored.

Can we make drugs that not only break/inhibit interactions between a protein and a ligand, but rather bestow new functionality? Nicolas Thomä explores molecular glue drugs, and their potential to make much needed medicines that were previously out of reach.