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bit.bio webinar technologynetworks 2nd May 2024

Uncovering the Glioma Microenvironment With In Vitro Neuronal Models

Gliomas are tumors resident in the central nervous system that account for over 33% of all brain tumors. The tumor microenvironment is a vast mix of excitatory and inhibitory neurons as well as glial cells, and a disruption of this delicate balance can lead to tumor-associated seizures. GABAergic neurons play a key role in these imbalances and are a key cell type for investigations into the glioma microenvironment.

In this webinar, you’ll hear from Dr. Brian Gill about his research into neuron–glioma interactions and how they contribute to seizures and tumoral growth. You will also learn about a neural co-culture platform to study excitatory–inhibitory neuron imbalances for the discovery of new drugs from Dr. Tony Oosterveen.

Attend this webinar to:

  • Gain a comprehensive understanding of how glioma alters crosstalk between different neuronal populations
  • Discover how excitatory and inhibitory neuronal populations contribute to the intense electrical activity observed in tumoral epilepsy
  • Uncover how precision reprogrammed human iPSC-derived ioGABAergic neurons can be applied to explore the glioma microenvironment
  • Learn about the use of a neural co-culture platform to study the modulation of neuronal networks by drugs

A picture of Dr. Brian Gill, MD
Dr. Brian Gill, MD
Assistant Professor of Neurological Surgery
Columbia University Irving Medical Center
A picture of Dr. Tony Oosterveen
Dr. Tony Oosterveen
Principal Scientist and CNS Lead, Neurobiology
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