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Detect Low Abundance Biomarkers in Murine Models

Credit: iStock

The ability to measure key immune mediators with high sensitivity enables the detection of low abundance biomarkers. This has the potential to revolutionize our understanding of autoimmune diseases when using murine models, since they are incapable of producing large samples for analysis.

In this interview, Dr. Cuong Nguyen explores how to leverage small sample volumes with sensitive multiplex cytokine measurements, using his research on the dynamics of Sjögren's syndrome as an example.

Download this whitepaper to discover expert insights into:

  • How animal models are used to elucidate disease pathogenesis and potential treatment avenues
  • Using a comprehensive panel to study an immunological process with volumes as low as 1 µL
  • Considerations for longitudinal studies, such as minimal sample volume
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