Researchers have identified an independent prognostic factor - cancer/testis antigen 45 (CT45) - and have begun to elucidate it's actions. CT45 is associated with extended disease-free survival for women with advanced ovarian cancer.

Stanford scientists have measured the human “exposome,” or the particulates, chemicals and microbes that individually swaddle us all, in unprecedented detail.

Researchers from the Department of Biochemistry and Molecular Biology at the UAB and from the United Kingdom, for the first time describe the mechanism used by cells to optimise protein production in stressful situations through the altering of tRNA abundance.

A growing number of life science businesses are turning to greater supply chain collaboration for benefits like accelerated time to market, improved quality, reduced risk and more rapid and widespread innovation. But while 68% of executives in this industry say active and meaningful engagement with suppliers is essential to success, far too many, over a third, struggle to implement it.

This article explores the current state of play within the area of cancer proteomics, highlights some of the techniques used to investigate the proteome, and looks at the impact of combining proteomics with other ‘omics’ in relation to cancer research.

The accurate identification of bacterial infections is necessary for the fight against antibiotic resistance. This procalcitonin assay is set to aid antibiotic stewardship and improve healthcare outcomes for sepsis patients.

Antimicrobials have revolutionized medicine by enabling treatments for diseases that would once have proven fatal, however,they have since proven to be a double-edged sword.

Scientists use Cryo-EM to solve the structure of the frontotemporal dementia-causing tau protein tangles.

Non-invasive liquid biopsies are set to change the landscape of how cancers are diagnosed and treated in the future. We explore how mass spectrometry is helping researchers discover protein biomarkers in blood and urine, highlight challenges around their validation – and find out how close they are to reaching the clinic.