timsTOF HT: Expand the capabilities of high-throughput, 4D-Proteomics™
The timsTOF HT, a novel 4th-generation TIMS (trapped ion mobility separation) XR cell and 14bit digitizer for even greater dynamic range, enhanced peptide coverage and more accurate quantitation, particularly in unbiased 4D plasma and tissue proteomics and epiproteomics.
“Mystery Gene” Ensures Final Form of Actin Protein Is Created
Researchers have discovered how a gene called ACTMAP is involved in the maturation of actin, one of the main components of the cell skeleton.
Oxytocin Has Heart “Healing” Properties
Researchers show that, in zebrafish and human cell cultures, oxytocin has an unsuspected function: it stimulates stem cells derived from the heart’s outer layer (epicardium) to migrate into its middle layer (myocardium) and there develop into cardiomyocytes, muscle cells that generate heart contractions.
Breaks in Non-Coding DNA Provide New Insights Into Brain Disorders
Researchers have identified how oxidative breaks form and are repaired in what scientists thought to be "junk" DNA.
Liquid Biopsy: Reading the Signs of Disease From Biofluid
Liquid biopsy is a novel diagnostic tool, which seeks for signs of disease from various biofluids. This article will explore recent developments in the liquid biopsy field and the impact they are making on patients.
A Conversation on Immunity
Dr. Jenna Macciochi is a lecturer in immunology at the University of Sussex, where her research centers on understanding the role that nutrition and lifestyle play in human immunity. Technology Networks sat down with Dr. Macciochi to ask: how can we really stay well? What has immunological research taught us about the effects of modern lifestyle on our bodies and what are some of the latest breakthroughs in this field?
A Degeneration of Trust
Recently, an expose article was published revealing a potential fabrication of data by prominent investigators of Alzheimer’s disease. In this op-ed piece, Michael Kinch explores the catastrophic impact of scientific fraud.
Why Biomarkers of Biological Age Could Be Misleading
Over the last decade there has been a prolific “boom” in aging and anti-aging research, extending beyond academic work into biotech and big pharma. A new study calls the biomarkers used to track the benefits of "anti-aging" regimens, and to calculate biological age, into question.
The Binomial Test
The Binomial test, sometimes referred to as the Binomial exact test, is a test used in sampling statistics to assess whether a proportion of a binary variable is equal to some hypothesized value. In this article, we explore the key features of this test and walk through an example test.
Connecting Laboratories With Data-Driven Automation Software
Download this guide to learn more about automated software and the latest solutions available.
Western Blot Troubleshooting Tips
Download this guide to discover tips and tricks on preparation and optimization, selecting the right controls, and blocking and washing.
Faster Approaches to Vaccine Design
Download this listicle to learn more about the technologies that have advanced vaccine design including reverse vaccinology 2.0, comparative and subtractive genomics, immunoproteomics and immunopeptidomics, and computational approaches.
Maintaining Batch-to-Batch Consistency
Download this listicle to learn more about optimizing reproducibility and batch consistency during biopharmaceutical development.