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10 Things We Didn't Know Last Week – 10 May 2019

List

A wrap-up of the biggest science news from the last 7 days.

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The Evolution of Proteomics – Professor Ruedi Aebersold

Article

Kicking off "The Evolution of Proteomics" series is a pioneer of proteomics, Professor Ruedi Aebersold. Aebersold's research in quantitative proteomics has helped shape our understanding of how proteins function, interact and are localized in both normal and diseased states.

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Proteomics Experts Unite for EPIC-XS

Blog

The European Proteomics Infrastructure Consortium providing access (EPIC-XS) consists of a network of experienced research groups that share one common goal: to facilitate the development and sustainability of proteomics explorations to researchers within the European Union. We spoke with Martina O’Flaherty from the EPIC-XS project office to learn more.

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Surprising Role for Protein in Tuning Human Skin Color
News

Researchers have found that opsin 3 -- a protein closely related to rhodopsin, the protein that enables low-light vision -- has a role in adjusting the amount of pigment produced in human skin, a determinant of skin color.

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“Metabolic Fingerprint” Could Help Treat, Diagnose and Prevent Cervical Cancer
News

Researchers at the University of Arizona have completed the first-of-its-kind study that could aid in the treatment, diagnosis and prevention of cervical cancer by identifying cervicovaginal metabolic signatures, or "fingerprints" that distinguish patients with HPV, pre-cancerous cervical conditions and cancer.

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How the Pursuit for Carbs Changed Mammals’ Genes
News

A new study is providing insight into how the pursuit of starch may have driven evolutionary adaptations in these and other hungry mammals.

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A Closer Look at How the Brain Controls Food Intake
News

Regardless of how much you exercise or how balanced your diet is, controlling your weight is more brain-related than you might have thought. In a recent study, researchers show for the first time in mice that the acyl-CoA-binding protein, or ACBP, has a direct influence on the neurons that allow rodents and humans to maintain a healthy weight.

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Tiny Variations in a Liver Cell Protein Affect Hep C Virus Replication
News

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection.

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Nanotubes Pave the Way for Huntington Protein
News

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists.

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The First Winners of the LEA

Article

The Lipidomics Excellence Award (LEA) was founded to strengthen life sciences through lipidomics. After reviewing the many high-quality submitted projects, the LEA jury has announced the three awardees.

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The Evolution of Proteomics - Dr Mikhail Savitski
Article

Dr Mikhail Savitski, the Team Leader and Head of the Proteomics Core Facility at the European Molecular Biology Laboratory, has made several impressive contributions to the proteomics field, including the development of thermal proteome profiling (TPP).

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The Evolution of Proteomics - Dr Evangelia Petsalaki
Article

Dr Evangelia Petsalaki is a Group Leader at the European Bioinformatics Group, where her research team study human cell signaling in health and disease conditions. Collaborating with teams specializing in MS, imaging and cell biology, their aim is to make both predictive and conditional models so they can anticipate what might happen in a biological network under different conditions.

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Cryo-EM Provides the Structural Blueprint for Protein Nanomachines
Article

We spoke to Cristina Paulino, Assistant Professor in high-resolution cryo-electron microscopy (cryo-EM) at the University of Groningen, to learn about the role cryo-EM plays in her group's work in the study of membrane protein structure and function.

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