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Proteomics Experts Unite for EPIC-XS

Blog

The European Proteomics Infrastructure Consortium providing access (EPIC-XS) consists of a network of experienced research groups that share one common goal: to facilitate the development and sustainability of proteomics explorations to researchers within the European Union. We spoke with Martina O’Flaherty from the EPIC-XS project office to learn more.

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Making Sense of Proteomic Data Pipelines

Infographic

Studying the proteome is not a simple task. This infographic summarizes the process by which complex proteomic data is gathered, streamlined and analyzed in a data pipeline.

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Interrogation of Single Cells Taken One Step Further With ECCITE-Seq
News

A new technique called ECCITE-seq allows researchers to perform high-throughput measurements of multiple modalities of information from single cells.

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Diversifying the Natural Building Blocks of Life
News

Using EBX reagents, researchers have converted the C-terminal carboxylic acid of peptides into a carbon-carbon triple bond - an alkyne (in chemical jargon a "decarboxylative alkynylation"). The alkyne moiety is a very valuable functional group that can be used to further modify the peptides.

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How Cells Keep DNA Tangle-free
News

A process that cells use to unravel knotted strands of DNA - resembling a method used to control climbing ropes - has been uncovered by scientists.

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High-risk Genes for Schizophrenia Identified
News

Using a unique computational "framework" they developed, a team of scientist cyber-sleuths has identified 104 high-risk genes for schizophrenia.

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Protein Structure Predictions With Deep-learning
News

Scientists have used a form of artificial intelligence known as deep learning to predict the 3D structure of effectively any protein based on its amino acid sequence.

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Blood Test for Detecting Pre-symptomatic Alzheimer's Disease is Refined
News

A research team have developed a method to detect the amyloid-beta (Aβ) peptide in human blood. They hope that their research will have implications in diagnosing and understanding the progression of Alzheimer's disease (AD).

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The Evolving Field of Cancer Biomarkers
Article

Given the complexity of cancer, it’s arguably unlikely that single molecules will work as clinically meaningful biomarkers for cancer. Today, biomarker discovery involves detecting patterns – characteristics or phenotypes that can be measured and monitored throughout a patient’s journey. Here, we look at two approaches being explored in this evolving field.

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Sensitivity vs Specificity
Article

When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.

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NASA Identical Twin Study Takes Our Understanding of Space Travel to the Final Frontier
Article

Identical male twins Scott and Mark Kelly - both (now retired) NASA astronauts – spent one year apart as Scott travelled to and inhabited the International Space Station (ISS), whilst Mark stayed at home on earth. Researchers have gained valuable insights from the study results as to the physiological effects of space travel.

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The Power of Proteogenomics in Precision Medicine
Article

Part of the "systems biology" trend, proteogenomics is expanding at an accelerating rate. In this article, we look at the approaches adopted in proteogenomics and explore how proteogenomics is changing the dynamics of precision medicine in oncology.

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Post-translational Modifications in Biopharmaceuticals
Article

This article provides insights on the impact of post-translational modifications of biopharmaceutical products on drug development and biotherapeutic formulation.

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Mass Spectrometry is Advancing Cancer Research in Leaps and Bounds
Article

From picking out cancerous tissue areas during diagnosis, to uncovering novel biomarkers of early detection, mass spectrometry has become an indispensable analytical technique in cancer research.

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