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Latest App Notes & Case Studies

Medical professional analyzing brain MRI scans on a computer screen for neuroimaging diagnostics
App Note / Case Study

Unlock Brain Tumor Insights With Imaging Mass Cytometry

This application focus explores how IMC can be applied to identify major cell populations that make up mouse brain matter.
Illustration of intricate neuronal networks, representing neurodegeneration research and synaptic connections
App Note / Case Study

Exploring Neurodegenerative Diseases With Imaging Mass Cytometry

This application note demonstrates how imaging mass cytometry (IMC) is transforming neurodegeneration research, providing detailed visualization of protein aggregates, neuron populations and inflammatory cell interactions.
3D visualization of protein interactions on a cell surface, illustrating mechanisms in assay development
App Note / Case Study

Gain Deeper Insights in Proteomics Research

This application note showcases how this robust, highly multiplexed platform supports novel biomarker discovery in drug development and aids in developing diagnostics for a wide range of critical diseases.
3D illustration of a protein binding to an aptamer, highlighting its role in assay development.
App Note / Case Study

Scale Up Proteomics With Precision

This application note examines an advanced proteomics platform designed to provide high precision across thousands of proteins, enabling reliable results even in large-scale and longitudinal studies.
Doctor holding a syringe and spiky model representing disease pathways and vaccine intervention.
App Note / Case Study

Advancing Proteomics Research Using Trapped Ion Mobility Spectrometry

This case study explores how TIMS is driving innovation in proteomics, enabling breakthroughs in biological research and clinical applications.
3d illustration of proteins in different colours
App Note / Case Study

High-Plex Protein Detection To Support Therapy Development

This app note highlights a multiplex immunofluorescence imaging solution for targeted spatial proteomics that provides several advantages over other spatial proteomic and transcriptomic technologies for biomarker studies.
High-throughput high-resolution data-independent acquisition workflow on an Orbitrap Exploris 480 mass spectrometer for accurate label-free quantitation
App Note / Case Study

Optimized Approaches for High-Throughput Protein Quantitation

This tech note explores the integration of automated sample preparation, robust LC-MS/MS analysis, and advanced data analysis software to achieve high-throughput and accurate label-free quantitation.
Protein
App Note / Case Study

Improving Complex Phosphopeptide Characterization

This app note highlights the use of electron-activated dissociation and collision-induced dissociation to enhance the fragmentation of peptides from casein tryptic digests.
mRNA Strand
App Note / Case Study

High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV

This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
Sequencing
App Note / Case Study

Automate Assembly Cloning Using a Liquid Handling Platform

This application note presents a case study where a manual cloning approach was adapted with an automated platform to expedite experiments on 96-well and 384-well plates.
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