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Latest App Notes & Case Studies

Doctor holding a syringe and spiky model representing disease pathways and vaccine intervention.
App Note / Case Study

Advancing Proteomics Research Using Trapped Ion Mobility Spectrometry

This case study explores how TIMS is driving innovation in proteomics, enabling breakthroughs in biological research and clinical applications.
3d illustration of proteins in different colours
App Note / Case Study

High-Plex Protein Detection To Support Therapy Development

This app note highlights a multiplex immunofluorescence imaging solution for targeted spatial proteomics that provides several advantages over other spatial proteomic and transcriptomic technologies for biomarker studies.
High-throughput high-resolution data-independent acquisition workflow on an Orbitrap Exploris 480 mass spectrometer for accurate label-free quantitation
App Note / Case Study

Optimized Approaches for High-Throughput Protein Quantitation

This tech note explores the integration of automated sample preparation, robust LC-MS/MS analysis, and advanced data analysis software to achieve high-throughput and accurate label-free quantitation.
Protein
App Note / Case Study

Improving Complex Phosphopeptide Characterization

This app note highlights the use of electron-activated dissociation and collision-induced dissociation to enhance the fragmentation of peptides from casein tryptic digests.
mRNA Strand
App Note / Case Study

High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV

This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.
Sequencing
App Note / Case Study

Automate Assembly Cloning Using a Liquid Handling Platform

This application note presents a case study where a manual cloning approach was adapted with an automated platform to expedite experiments on 96-well and 384-well plates.
App Note / Case Study

Streamlined Detection and Characterization of Mitochondrial Toxicants

This app note highlights an assay that enables streamlined, sensitive detection and characterization of mitochondrial toxicants.
Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry
App Note / Case Study

Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry

This application note presents a highly sensitive signature peptide quantification workflow using cutting-edge accurate mass spectrometry technology.
Peptide protein
App Note / Case Study

High Sensitivity Immunopeptidomics Using Mass Spectrometry

This application note demonstrates how timsTOF and single-cell proteomics (SCP) approaches can be combined to create a robust and sensitive immunopeptidomics workflow.
Easy Set-Up for Protein Crystallization Experiments
App Note / Case Study

Easy Set-Up for Protein Crystallization Experiments

This app note highlights how a handheld electronic pipette can help researchers save time and increase homogeneous crystal growth.
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