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Latest App Notes & Case Studies

Analysis of Lipid Nanoparticle Composition content piece image
App Note / Case Study

Analysis of Lipid Nanoparticle Composition

In recent years, interest in lipid nanoparticle (LNP) research has increased due to promising opportunities for RNA-based therapy and gene-editing technology, and LNPs are showing promise as nucleic acid delivery vehicles in the pharmaceutical industry.
Proteomics at the Single-Cell Level content piece image
App Note / Case Study

Proteomics at the Single-Cell Level

Single-cell proteomics is a rapidly developing field with the potential to make important contributions to understanding cellular heterogeneity.
Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Preparation content piece image
App Note / Case Study

Feel the Need, the Need for Speed: Advances in RapidFire-MS Analyses for Faster, Larger Runs with Less Sample Preparation

Download this free application focus to learn more about how Agilent's latest RapidFire 400 mass spectrometry system.
Guide RNA Production content piece image
App Note / Case Study

Guide RNA Production

Over the past decade there has been a widespread adoption of CRISPR/Cas9-based methods for genome editing in biological systems ranging from cultured cells to entire animals.
App Note / Case Study

Label-Free Single Cell Proteomics Workflow

Label-Free Single Cell Proteomics Workflow With the CellenONE Platform and the TimsTOF SCP
Get a High-Resolution View of Your Lipid Nanoparticles content piece image
App Note / Case Study

Get a High-Resolution View of Your Lipid Nanoparticles

Lipid nanoparticles (LNP) play a key role in effectively protecting and transporting mRNA to target cells in mRNA-based vaccines and therapeutics. To ensure the quality and safety of LNP, lipid components and associated impurities/degradants need to be carefully characterized in raw materials and formulation.
TIMScore With PaSER: Exploiting the CCS-Dimension content piece image
App Note / Case Study

TIMScore With PaSER: Exploiting the CCS-Dimension

Download this app note to discover a solution that boosts the numbers of proteins, peptides and PSMs in complex datasets as well as increases protein sequence coverage substantially.
Purification of Single-Stranded RNA Oligonucleotides Using High-Performance Liquid Chromatography content piece image
App Note / Case Study

Purification of Single-Stranded RNA Oligonucleotides Using High-Performance Liquid Chromatography

A crucial step in any pharmaceutical production is the purification of the product. The purification of oligonucleotides (ONs) can be particularly challenging because of the high similarity of target and impurities.
A Tale of Two End-to-End Targeted Metabolomics Workflows content piece image
App Note / Case Study

A Tale of Two End-to-End Targeted Metabolomics Workflows

Download this application focus to learn more about two novel, sensitive, targeted metabolomics solutions.
Phosphorylated Peptide Post-Translational Modification Site Localization and Isomer Differentiation content piece image
App Note / Case Study

Phosphorylated Peptide Post-Translational Modification Site Localization and Isomer Differentiation

However, PTM site localization and quantification of phosphopeptides by collision induced dissociation MS/MS can be challenging, and phospho-peptides can exhibit a partial neutral loss of the phospho group.
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