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A Rapid and Robust Solution for Cellular Response Characterization

Cancer cells under a microscope, showing abnormal growth and division.
Credit: iStock

T cells are pivotal in the immune system's response to cancer, however, challenges such as poor tumor recognition and penetration into solid tumors hinder their efficacy.

Novel immunotherapies, including tumor infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T cells, have been developed to enhance T-cell responses against cancer. 

This app note explores the use of an assay to facilitate rapid monitoring of T-cell function and simultaneous assessment of cell phenotype, activation markers, proliferation, viability and cytokine secretion. 

Download this app note to discover insights into the:

  • Concentration-dependent effects of therapies
  • Impact of environmental factors on TILs
  • Antigen specificity of CAR T cells
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