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Antibody-Oligonucleotide (Ab-Oligo) Conjugate Preparation and Applications

Antibody-oligonucleotide (Ab-Oligo) conjugates have been used in numerous applications from diagnostics to therapeutics and were developed through an unmet need for precise and efficient detection of low-abundance proteins. Ab-Oligo conjugates have since played a significant role in enhancing an extensive range of biological techniques that include immunological and proteomic research, biomarker discovery, clinical diagnostics – including point-of-care, as well as other novel techniques. Antibodies can be readily conjugated to oligonucleotides via their amino acid residues, making them suitable for most in vitro applications, as they possess several functional groups.

Download this application note to learn about the applications and benefits of using , assay development and best preparation techniques for your antibody-oligonucleotide conjugates including:

- Immuno-PCR

- Proximity Ligation Assays

- Electrochemical Proximity Assays