Large-Scale Plasma Proteomics With PASEF

Plasma and serum samples are of high interest for biomarker research due to their content and accessibility. Nonetheless, their large dynamic range of protein concentrations make in-depth proteome quantification a challenge.

While depleting abundant proteins can facilitate the detection of low-concentration biomarkers, such methods can be labor-intensive, costly and can result in sample loss. 

Discover how parallel accumulation, serial elution and fragmentation (PASEF) can support researchers to achieve accurate large-scale plasma proteomics. 

Download this app note to discover:

• High-throughput and precise quantification methods for hundreds of proteins 
• Reliability and accuracy without sample depletion
• Greater analytical depth in less than half the turnover time