We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Phosphorylated Peptide Post-Translational Modification Site Localization and Isomer Differentiation
Application Note

Phosphorylated Peptide Post-Translational Modification Site Localization and Isomer Differentiation

Phosphorylated Peptide Post-Translational Modification Site Localization and Isomer Differentiation
Application Note

Phosphorylated Peptide Post-Translational Modification Site Localization and Isomer Differentiation

Protein phosphorylation is an important post-translational modification (PTM) as it is involved in a large variety of dynamic cellular processes. However, PTM site localization and quantification of phosphopeptides by collision induced dissociation MS/MS can be challenging, and phospho-peptides can exhibit a partial neutral loss of the phospho group.

Download this app note to learn how electron activated dissociation fragmentation: 

  • Shows promising performances for the robust and accurate quantification of labile PTMs
  • Generates strong and distinct PTM site localization ions
  • Offers a detailed characterization of the modified peptides of interest
Advertisement