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Latest Articles

The Evolving Field of Cancer Biomarkers
Article

Given the complexity of cancer, it’s arguably unlikely that single molecules will work as clinically meaningful biomarkers for cancer. Today, biomarker discovery involves detecting patterns – characteristics or phenotypes that can be measured and monitored throughout a patient’s journey. Here, we look at two approaches being explored in this evolving field.

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Sensitivity vs Specificity
Article

When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.

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NASA Identical Twin Study Takes Our Understanding of Space Travel to the Final Frontier
Article

Identical male twins Scott and Mark Kelly - both (now retired) NASA astronauts – spent one year apart as Scott travelled to and inhabited the International Space Station (ISS), whilst Mark stayed at home on earth. Researchers have gained valuable insights from the study results as to the physiological effects of space travel.

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The Power of Proteogenomics in Precision Medicine
Article

Part of the "systems biology" trend, proteogenomics is expanding at an accelerating rate. In this article, we look at the approaches adopted in proteogenomics and explore how proteogenomics is changing the dynamics of precision medicine in oncology.

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Post-translational Modifications in Biopharmaceuticals
Article

This article provides insights on the impact of post-translational modifications of biopharmaceutical products on drug development and biotherapeutic formulation.

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Mass Spectrometry is Advancing Cancer Research in Leaps and Bounds
Article

From picking out cancerous tissue areas during diagnosis, to uncovering novel biomarkers of early detection, mass spectrometry has become an indispensable analytical technique in cancer research.

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Addressing the Underrepresentation of Women in Science
Article

We recently spoke with Jessica Wade, PhD, a physicist at Imperial College London to learn more about her extraordinary efforts to raise the profile of female scientists and other underrepresented groups in science.

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NMR Spectroscopy and Databases for the Identification of Metabolites
Article

Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique used to identify and quantify the constituents of complex mixtures. Here, we take a look at how researchers are using NMR spectroscopy and databases in the emerging field of metabolomics.

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Incentivizing Drug Development for Rare Diseases
Article

On Rare Disease Day 2019, we discuss how regulatory incentives are necessary for encouraging rare disease drug development, and share the testimonial videos from this year's international campaign.

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World Yoga Day: Finding the OM in GenOMics
Article

A recent climb in the number of people taking up a regular yoga or meditation practise has seen the terms “downward dog” and “tree pose” enter the everyday vocabulary of many. Today, on World Yoga Day, people come together across the world to celebrate the unity that yoga brings. However, from a scientific perspective, what evidence exists that supports the benefits of a regular yoga and meditation practise?

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