Latest Articles

Novel UPLC - MS/MS Method Detects Mycotoxin, Ochratoxin A, in Food Products
Article

A team of scientists have designed a simplified, sensitive test that can identify the mycotoxin ochratoxin A in food products, which can cause serious harm if ingested.

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Rapid Detection of Designer Drugs Presents Challenges for Law Enforcement and Forensic Toxicology
Article

The rise of designer drugs is creating new challenges for both law enforcement and forensic toxicology laboratories, leading to new methods to identify and combat the often-deadly substances.

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Types of Pollution: Have You Considered Pharmaceutical Waste?
Article

Despite regulation and legislation regarding the methods by which pharmaceutical companies must treat waste water, reports indicate that manufacturers are continuing to discharge untreated or inappropriately treated waste into the environment. The problem is having devastating impacts on human health, the environment and antimicrobial resistance is soaring.

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Capillary Electrophoresis-Mass Spectrometry – The Coming of Age for a Powerful Technique
Article

Capillary electrophoresis-mass spectrometry (CE-MS) has remained in the shadows for decades. However, this powerful separation technique is now enjoying a renaissance, with academic and industrial scientists keen to exploit its key advantages. We spoke to some of its most ardent fans to explore a variety of the latest research and clinical applications.

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The Legos of Life: Primordial Proteins Unveiled
Article

Researchers have worked out the structure of protein progenitor molecules that existed billions of years ago, which may have modern-day uses.

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Practical Guidance for the Confident Application of Differential Scanning Calorimetry
Article

In this article, we provide practical guidance for the application of differential scanning calorimetry (DSC), a core technique for studying the stability and higher order structure (HOS) of proteins. We explain how DSC works, and highlight good practice for ensuring optimal data quality. The interpretation and value of the resulting data is also discussed.

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Protein Biotherapeutics: Mass Spectrometry Analysis
Article

Mass spectrometry has evolved as a prevailing technique for both the characterization of biotherapeutics and identification of protein variants and post-translational modifications.

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Lipidomics Opens Doors to Understanding Stem Cell Differentiation
Article

It has long been known that the fats we consume in our diet can have an impact on our health. However, their implications on cell differentiation has not previously been understood. We spoke to Professor Ilya Levental about his group's exciting work in this field, the role of lipidomics and how this may affect the future of healthcare.

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Protein Purification: Chromatography and Scalability in Biopharma
Article

Prof. Giorgio Carta provides us with extraordinary insight into the current state of play, factors to consider when 'scaling up’ separation processes, and general challenges and developments when applying chromatographic techniques to bioprocesses.

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Quantitative Proteomics in Precision Medicine
Article

Medicine has been moving away from a "one-size-fits-all" approach towards predictive, preventive and treatment strategies tailored to the individual - precision medicine. Quantitative proteomics is playing an important part in this process but there are still some areas in which improvements must be seen before assays are likely to be routinely available to clinicians and patients.

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