Latest Articles

The Lipidomics Excellence Award (LEA) was founded to strengthen life sciences through lipidomics. After reviewing the many high-quality submitted projects, the LEA jury has announced the three awardees.

Dr Mikhail Savitski, the Team Leader and Head of the Proteomics Core Facility at the European Molecular Biology Laboratory, has made several impressive contributions to the proteomics field, including the development of thermal proteome profiling (TPP).

Dr Evangelia Petsalaki is a Group Leader at the European Bioinformatics Group, where her research team study human cell signaling in health and disease conditions. Collaborating with teams specializing in MS, imaging and cell biology, their aim is to make both predictive and conditional models so they can anticipate what might happen in a biological network under different conditions.

Kicking off "The Evolution of Proteomics" series is a pioneer of proteomics, Professor Ruedi Aebersold. Aebersold's research in quantitative proteomics has helped shape our understanding of how proteins function, interact and are localized in both normal and diseased states.

We spoke to Cristina Paulino, Assistant Professor in high-resolution cryo-electron microscopy (cryo-EM) at the University of Groningen, to learn about the role cryo-EM plays in her group's work in the study of membrane protein structure and function.

Given the complexity of cancer, it’s arguably unlikely that single molecules will work as clinically meaningful biomarkers for cancer. Today, biomarker discovery involves detecting patterns – characteristics or phenotypes that can be measured and monitored throughout a patient’s journey. Here, we look at two approaches being explored in this evolving field.

When developing diagnostic tests or evaluating results, it is important to understand how reliable those tests and therefore the results you are obtaining are. By using samples of known disease status, values such as sensitivity and specificity can be calculated that allow you to evaluate just that.

Identical male twins Scott and Mark Kelly - both (now retired) NASA astronauts – spent one year apart as Scott travelled to and inhabited the International Space Station (ISS), whilst Mark stayed at home on earth. Researchers have gained valuable insights from the study results as to the physiological effects of space travel.

No microbe is an island. Understanding how they interact with each other and their surrounding environment is important to harness their beneficial properties and combat harmful behavior. We spoke to Professor Ariane Briegel about the important role of cryo-EM in these studies.

Part of the "systems biology" trend, proteogenomics is expanding at an accelerating rate. In this article, we look at the approaches adopted in proteogenomics and explore how proteogenomics is changing the dynamics of precision medicine in oncology.