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Landmark Study Solves Structure of Dementia Protein

Article   Jul 05, 2017 | Adam Tozer PhD, Technology Networks

Structure of Tau Filaments from Alzheimer’s Brain Solved by Cryo-EM

Tau filament structures, rendered in blue and white. In the background, a photomicrograph of a Bodian silver-stain preparation shows a neuron from the cerebral cortex of an individual affected by Alzheimer disease. The cytoplasm around the nucleus contains a flame-shaped neurofibrillary tangle. The Tau filaments appear to wrap around the neuron.

Adam Tozer PhD

Science Writer




Cell Signaling in Cancer


This article discusses the relationship between cell signaling and cancer, highlights key signaling pathways involved in cancer, and explores how critical mediators of aberrant signaling can be turned into therapeutic targets for cancer.


Shedding Light on Wine Fraud with NMR Fingerprinting


Wine forgery, including adulteration, counterfeiting (e.g. mislabeling/misrepresentation) and intellectual property infringement, takes place on a global scale, but is on the rise in central Europe. To help in the fight against fraud, the industry are turning to NMR fingerprinting to stamp out the problem.


A (Lab)Step Towards Reproducible Science


The reproducibility crisis is holding back science. London-based Labstep, a start-up out of Oxford University, think that their tool can help make science more open and reproducible. That claim has now been given some concrete evidence with the announcement that the research contingent of the MRC Unit The Gambia at LSHTM will be trialling Labstep across their Banjul-based facility.



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