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Blog

Visualizing Drug Targets With Ligand Express
Blog

In the development of a therapeutic pharmaceutical agent, it is crucial to understand the on- and off-target effects the molecule may have within the body. Cyclica's Ligand Express® is a cloud-based platform that screens small-molecule drugs against structurally-characterized proteins, or "proteomes" to determine polypharmacological profiles. We spoke with Naheed Kurji, President & CEO, and Andreas Windemuth, Chief Science Officer, from Cyclica to find out more.

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Releasing the Handbrake on Exosome Applications
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Despite the great excitement about exosomes and their huge diagnostic and therapeutic potential, the technology needed to advance this work is lacking. We spoke to Jim West, CEO of Clara Biotech, who tells us how his team is working to fill that gap.

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Proteogenomics, Precision Medicine and Oncology
Blog

Major advances have occurred in the fields of proteomics and genomics over recent years. Now, scientists are utilizing the technologies from each approach collectively in a novel research area named proteogenomics. We spoke with Alexzander Asea, Professor and Director at Precision Therapeutics Proteogenomics Diagnostics Center, University of Toledo, to learn more about the applications of proteogenomics in precision medicine.

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Calculating Gestational Age With Metabolomics
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Researchers have developed a mathematical model that may offer an alternative to relying on ultrasound information for calculating gestational age. The model, utilizing a "metabolomic fingerprint" approach, may overcome barriers in preterm death research.

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Proteomics Experts Unite for EPIC-XS
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The European Proteomics Infrastructure Consortium providing access (EPIC-XS) consists of a network of experienced research groups that share one common goal: to facilitate the development and sustainability of proteomics explorations to researchers within the European Union. We spoke with Martina O’Flaherty from the EPIC-XS project office to learn more.

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Tiny Protein Has Huge Potential in CRISPR
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Last year the smallest CRISPR protein, Cas14 was discovered. We spoke to the scientists that made the discovery, Lucas Harrington, at Mammoth Biosciences, to learn more about Cas14.

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Take a Good Book Around
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Our recent social media poll on "book recommendations for scientists" provided an incredible response. We decided to collate this information and give you the perfect excuse to treat yourself to a new read. Enjoy!

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Microfluidics Solutions to Proteomics Problems
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Microfluidic platforms are becoming commonplace across biological science. To find out more about how microfluidic technology is revolutionizing protein analysis, we spoke to Tuomas Knowles, Founder and Chief Scientific Officer, Fluidic Analytics.

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Brain Injury Diagnosed With Single Drop of Blood: a Follow-up
Blog

What do biomarkers and a 1990s TGIF party have in common? Find out here...
TBIcheck is a rapid point-of-care diagnostic device that detects biomarkers indicative of mild traumatic brain injury. To find out more, we spoke with the head of the Biomedical Proteomics Group, Jean-Charles Sanchez.

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The Liquid Biopsy Trends Transforming Cancer Detection and Treatment
Blog

Liquid biopsy is a less invasive approach compared to traditional surgical biopsies. By collecting a simple blood sample and analyzing circulating tumor DNA (ctDNA), cancer researchers and healthcare professionals can access a myriad of information about a patient’s tumor.

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