Blog
How Native MS and Charge Algorithms Can Improve Protein Analysis
BlogNative Mass Spectrometry (MS) can be used to examine proteins in their natural, folded forms. In this blog, Marshall Bern, Ph.D., the Vice President of Research and Co-Founder of Protein Metrics, discusses how advances in this technique are being paired with cutting-edge charge deconvolution algorithms to improve analysis of antibodies and plasma glycoproteins.
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Cinderella and Mass Spectrometry: Insightful Multi-Dimensional Data Analysis
BlogProteomics is a powerful technology for analyzing low-abundance proteins for disease research. But it’s stalled by imprecise and often irreproducible data analysis. Here, David Chiang, Founder of Sage-N Research, explains how his company uses multidimensional separation to improve peptide identification in MS/MS.
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Newly Discovered Biomarker Could Help Diagnose Hearing Loss Earlier
BlogIn collaboration with UConn, Sensorion have identified the first potential biomarker for noise-induced hearing loss, findings which were recently presented at the 53rd American Neurotology Society Annual Spring Meeting.
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Data-Independent Acquisition: A Superior Technique in Mass Spectrometry?
BlogWhilst Mass Spectrometry is undoubted in its status as a central part of the proteomics toolkit, there is still debate about the way that MS data should be acquired and analyzed. Here, we talk to Florian Marty, Director Global Product Support at Biognosys AG, about why he believes that data-independent acquisition is a superior acquisition technique.
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New Method to Rule out Early Stage Lung Cancer
BlogWe spoke to Dr Albert Luderer, CEO of Integrated Diagnostics to learn about the challenges of diagnosing lung nodules as benign or malignant, and how the Xpresys Lung 2 liquid biopsy test can help improve this process.
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Revolutionizing the World of Pipetting
BlogNecessity is the mother of invention, and nowhere is this more clearly demonstrated than in the laboratory. We caught up with Alex Studer, VP of Marketing and Innovation at INTEGRA Biosciences, to discuss the company’s aim to transform the world of pipetting.
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Advances in Analytical Technology: Deciphering Complex Matrices
BlogWith justice and health in the balance, modern forensic toxicology drug testing labs are expected to detect and quantify a wide range of drugs and metabolites, from Fentanyl to novel psychoactive substances (NPS), at very low levels in biological matrices. The drug concentrations also need to be correlated with the impairment of the individual with absolute certainty, but labs face increasing pressures due to growing caseloads, sample backlogs, and budget restrictions.
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Building in Purity
BlogLaboratories rely on the constant provision of high quality water for a variety of purposes, from glass washing to reagent preparation and instrumental analysis. It is all too easy to take this valuable commodity for granted yet, behind the scenes, a great deal of thought goes into designing a facility that reliably and cost-effectively provides water of the required quality on a round the clock basis.
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Carrying the Torch for Scientific Glassblowing
BlogDespite the important role glass plays in science, the skill to develop the glassware is in decline. Scientific glassblowing has now been classed as an endangered craft by The Radcliffe Trust.
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Faster, More Efficient Proteomic Analysis
BlogWe spoke to Dr Gary Kruppa, Vice President Proteomics at Bruker Daltonics, about PASEF, a powerful new analysis technique which promises to maximize the potential of proteome analysis using LC-MS.
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