Thermo Scientific™

Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer

Catalog number: IQLAAEGAAPFADBMBHQ
Thermo Scientific™

Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer

Catalog number: IQLAAEGAAPFADBMBHQ

Excel at the most challenging of applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, as well as MSn analysis of small molecules with the new Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer. This system incorporates the brightest ion source, a segmented quadrupole mass filter with improved selectivity and ion transmission, Advanced Vacuum Technology for improved ion transmission to the Thermo Scientific™ Orbitrap™ mass analyzer, and ETD HD, a higher-capacity ETD fragmentation. Latest innovations include the Advanced Peak Determination (APD) algorithm for improved data-dependent experiments and two new hardware options: UVPD, a new fragmentation technique achieved with a 213 nm UV laser and 1M, which provides 1,000,000 FWHM ultra-high resolution for improved structural elucidation and quantitation of isobaric compounds.

 
Catalog Number
IQLAAEGAAPFADBMBHQ
Unit Size
Each
Description
Orbitrap Fusion Lumos Tribrid Mass Spectrometer
Price (USD)
Full specifications
TypeOrbitrap LC-MS
DescriptionOrbitrap Fusion Lumos Tribrid Mass Spectrometer
Max. ResolutionUp to 500,000 at m/z 200
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Easy Internal Calibration
Price (USD)
Full specifications
TypeEasy Internal Calibration
DescriptionEasy Internal Calibration
Unit SizeEach
Catalog Number
Unit Size
Each
Description
Easy Electron Transfer Dissociation (includes Easy-IC)
Price (USD)
Full specifications
TypeEasy Electron Transfer Dissociation
DescriptionEasy Electron Transfer Dissociation (includes Easy-IC)
Unit SizeEach
Showing 3 of 3
Catalog NumberSpecificationsUnit SizeDescriptionPrice (USD)
IQLAAEGAAPFADBMBHQFull specifications
EachOrbitrap Fusion Lumos Tribrid Mass SpectrometerRequest A Quote
TypeOrbitrap LC-MS
DescriptionOrbitrap Fusion Lumos Tribrid Mass Spectrometer
Max. ResolutionUp to 500,000 at m/z 200
Unit SizeEach
FETD2-10001Full specifications
EachEasy Internal CalibrationRequest A Quote
TypeEasy Internal Calibration
DescriptionEasy Internal Calibration
Unit SizeEach
FETD2-10002Full specifications
EachEasy Electron Transfer Dissociation (includes Easy-IC)Request A Quote
TypeEasy Electron Transfer Dissociation
DescriptionEasy Electron Transfer Dissociation (includes Easy-IC)
Unit SizeEach
Showing 3 of 3
Orbitrap Fusion Lumos Tribrid MS features:
  • Novel high-sensitivity API interface combines a High Capacity Transfer Tube and an Electrodynamic Ion Funnel for increased ion flux and lower limits of detection
  • Advanced Active Beam Guide to prevent neutrals and high velocity clusters from entering the resolving quadrupole
  • Advanced Quadrupole Technology combines high selectivity and efficiency of transfer for selected ions symmetrically across the isolation window
  • Advanced Vacuum Technology improves transmission of high molecular weight ions to the Orbitrap analyzer
  • Novel ETD HD—high dynamic range ETD provides significantly increased fragment ion coverage
  • Advanced Peak Determination (APD) - a new algorithm for improved precursor determination in data-dependent experiments, resulting in a large increase in identification of unique peptides and experimental throughput
  • Tribrid architecture includes a quadrupole mass filter, linear ion trap and an Orbitrap mass analyzer for maximal duty cycle due to a high degree of parallelization of various instrument operations
  • Ultrahigh resolving power up to 500,000 FWHM, with isotopic fidelity up to 240,000 FWHM at m/z 200
  • Acquisition rates of up to 20 Hz for both Orbitrap and linear ion trap MSn analyses
  • Full parallelization of MS and MSn analyses with intelligent ADAPT™ (All Dynamically Available Parallelizable Time) technology
  • Synchronous Precursor Selection (SPS) for MS and MSn experiments significantly increases the number of peptides and proteins identified and improves quantitative accuracy when using isobaric mass tags
  • Flexibility of fragmentation — CID, HCD and optional ETD and EThcD available at any stage of MSn with detection in either the Orbitrap or linear ion trap detector enables detailed structural determination of metabolites, glycans, and other small molecules
  • Universal Method provides maximal peptide identification without method optimization for samples of unknown concentration, reducing sample and instrument time requirements for routine peptide identification experiments
  • Intuitive and flexible drag-and-drop user interface simplifies method development and enables unique and complex workflows
  • Optional upgrades include IC, ETD, UVPD, and 1M:
    • Easy-IC - internal calibration improves mass accuracy
    • Easy-ETD - electron transfer dissociation for fragmentation of multiply charged precursors such as post-translationally modified peptides and intact proteins
    • UVPD - ultraviolet photodissociation for a wide variety of precursor ions including lipids, peptides, and intact proteins; unique to the Orbitrap Fusion Lumos Tribrid MS
    • 1M - 1,000,000 FWHM at m/z 200 ultra-high resolution improves structural elucidation and quantitation of isobaric compounds

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text