ADME in Drug Discovery
Infographic Aug 15, 2019 | by Laura Elizabeth Lansdowne, Science Writer, Technology Networks
Pharmacokinetics is the term used to describe the movement of a drug into, through and out of the body. The kinetics of a drug can be split into four phases – absorption, distribution, metabolism, excretion – also known as “ADME”.
ADME properties directly affect the activity of a drug, therefore, it is important to “optimize” the properties of drug candidate to ensure it is as effective as possible.
Download this infographic to learn about:
- The ways to deliver a drug to the body
- The key factors affecting distribution of a drug
- Drug metabolism and interactions
- The different ways a drug can be excreted from the body
Over recent years, the number of newly approved drugs brought to market has continued to decrease. Many drugs fail due to the fact they do not show efficacy at specific stages of the drug development pipeline, typically Phase II or Phase III. Subsequently, the pharmaceutical industry is facing pressures to optimize the drug discovery phase of the drug development pipeline, to avoid late-stage failures, and streamline the process. One approach to doing this is by adopting automation.READ MORE
Cryopreservation, the use of very low temperatures and cryoprotectants to preserve structurally intact cells and tissues, is essential to many areas of research and medicine. Find out why cryopreservation is used, how cryoprotectants reduce cell shrinkage, and learn about the therapies dependent on successful cryopreservation.READ MORE