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Anxiety Could Be Aging Your Body at the DNA Level
Researchers found that cumulative exposure to disadvantaged neighborhoods predicted faster epigenetic aging across three biological clocks. Emotional distress, particularly anxiety, mediated part of this effect.
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Microfluidic Device Cuts Protein Sample Use in X-Ray Experiments by 97%
Researchers have developed a device that cuts protein sample consumption by as much as 97% while still producing high-quality structural data.
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Protein Inhibition Improves Memory in Alzheimer's Model
New research has found that inhibiting a protein called PTP1B improves learning and memory in a mouse model of Alzheimer's.
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Experimental Pill Cuts LDL Cholesterol by Up to 60%
Phase 3 trial results show enlicitide, a once-daily oral PCSK9 inhibitor, cut LDL cholesterol by about 60% in high-risk patients already on statins. The pill could expand cholesterol treatment access if FDA approval leads to widespread adoption.
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Cancer Cell Metabolism Plays a Critical Role in Immunotherapy Response
Researchers have mapped lung cancer "neighborhoods", finding that cell metabolism is key for determining immunotherapy response.
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How Cells Keep Genes in Check Without a Key Epigenetic Tool
Researchers showed that in C. elegans, the protein MBD-2 regulates genes through repressive histone marks rather than DNA methylation. This alternative epigenetic mechanism preserves gene control despite evolutionary loss of 5mC.
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Why Do Some Neurons Resist Alzheimer’s Damage?
Researchers found that a protein called CUL5 helps neurons eliminate tau, reducing their vulnerability to neurodegeneration.
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Bacteria Have a Built-In Virus Sensor and Kill Switch
Researchers discovered a bacterial protein that detects phage infection and forms membrane pores to kill the host cell before viruses replicate. Structural studies showed Rip1 binds phage proteins and assembles into rings that rupture membranes.
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How Tau Tangles Form and Spread
New research into how tau tangles form and spread paves the way toward a neuronal vaccine that stops neurodegeneration before it can spread.
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Diagnostic Device Enables Non-Invasive Monitoring of Glioblastoma
UQ researchers have opened a "window to the brain" with a new diagnostic device that can determine how deadly brain tumours respond to treatment from a simple blood test.
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