Discrepancies in the Reference Human Genomes Are Identified
Researchers have identified genetic variant discrepancies between the two human reference genomes, creating guidance for laboratories to take advantage of an improved human reference genome.
Specialized Bacteria Make a Meal From DNA on the Seafloor
Researchers have discovered several bacteria from the Atlantic Ocean that use DNA as a food source.
Drug Targets Pancreatic Tumors Harboring Mutant KRAS
Researchers have demonstrated that pancreatic cancer patients with mutant KRAS-addicted tumors could benefit from treatment with a CDK inhibitor.
Vitamin D Deficiency Increases Addiction to Sunseeking... and Opioids
According to a study, vitamin D deficiency strongly exaggerates the craving for and effects of opioids, potentially increasing the risk for dependence and addiction.
Polyphenols Found in Chocolate and Wine Important to Soil Microbes Too
A research team has uncovered new insights into the role of polyphenols in the soil microbiome. The updated theory is that soils can be food sources for the microbes that live there.
Bacteria Hijack Phage of Competitors To Defeat Them
Scientists were able to show for the first time how Pseudomonas bacteria use a self-produced signal molecule to manipulate phages in a competing bacterial strain selectively to defeat their enemy. This targeted control of phages provides entirely new biotechnological and therapeutic approaches.
New Quantum Microscope Reveals Biological Detail Otherwise Impossible To See
Researchers have created a quantum microscope that can reveal biological structures that would otherwise be impossible to see.
SARS-CoV-2 Protease Cuts Human Proteins
Researchers have found targets of papain-like protease in the human proteome, including proteins involved in cardiovascular function, blood clotting and inflammation.
Movements of Nucleosomes Captured in Atomic Detail
Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in Münster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA opens while it is tightly wrapped around the proteins that package our genome.
Elemental Iron and Copper Found in the Brains of People With Alzheimer’s Disease
A new study identifies the presence of the elemental metals iron and copper within plaques taken from the brains of people with Alzheimer’s disease (AD).