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APC Protein Deletion Disrupts Cell Signalling and Could Cause Autism
NewsResearchers show deletion of the protein APC in progenitor cells leads to massive disruption of brain development and a signaling cascade previously linked to genes associated with autism.
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Mechanism of ApoE4 Gene Toxicity in Alzheimer's Disease Neurodegeneration Solved
NewsApoE4 exacerbates the brain damage caused by toxic tangles of Alzheimer's-associated protein, tau.
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New Method to Separate Mirrored Molecules Could Lead to Safer Drugs
News Sep 25, 2017The Dionne lab is developing an optical filter to sort chiral molecules, which could lead to purer and safer drugs and agrichemicals.
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Cancer Cells’ Energy Source Blocked by Natural Compound
News Sep 22, 2017Researchers have not only untangled an unusual wiring system that cancer cells use for carbohydrate metabolism, but also identified a natural compound that appears to selectively shut down this system in laboratory studies.
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Machine Learning to Increase the Pace of Brain Imaging Analysis
News Sep 21, 2017New approach could allow doctors or researchers to quickly identify the data they need, and then rapidly fill in the fine details, making the process faster and more accurate.
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SCIEX Receive Science and Technology Award at HUPO 2017
News Sep 21, 2017Two researchers from SCIEX received the HUPO 2017 award at the 16th Human Proteome Organization World Congress in Dublin, Ireland.
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Sharpest Image of Alzheimer’s Fibrils Shows Previously Unknown Details
News Sep 20, 2017The fibrils of the body's own amyloid beta (Aβ) protein are the main constituent of Alzheimer's disease-related and characteristic pathological protein deposits in the brain.
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CRISPR Reveals the Sugary Secrets of the Cancer-related Notch Protein
News Sep 19, 2017New research shows that the fucose and glucose modifications serve as quality-control markers that allow Notch to be transported to its final destination in the cell membrane.
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Developing a Gene Therapy for Deaf Patients
News Sep 19, 2017OSU researchers have taken an important step toward gene therapy for deaf patients by developing a way to better study a large protein essential for hearing and finding a truncated version of it.
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Discovery Provides Hope for New Vaccine Against Flesh-eating Bacteria
News Sep 19, 2017Researchers at Houston Methodist have solved a 100-year-old mystery, providing them a possible key to unlock a pathway for treating diseases caused by flesh-eating bacteria.
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Metabolic Classification of Human Hepatoblastoma Uncovered
News Sep 18, 2017EPFL scientists have now found metabolic differences between hepatoblastoma subtypes, and identified several biomarkers that can help obtain more accurate subtyping of the disease.
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Limiting Calorie Intake Slows Biological Aging in Animal Models
News Sep 14, 2017The new study links life-span to the epigenetic clock, and demonstrates that this clock is a useful biomarker to study aging.
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