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A strand of DNA.
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Toxic Protein May Be Cause of Two Rare Genetic Disorders

A toxic protein called DUX4 has been identified as a potential cause of two very different rare genetic disorders.
Expression of the microprotein in the mitochondria and in the nucleus.
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Microproteins Emerged Out of Nowhere

Bioinformatic gene analyses have revealed that most human microproteins developed millions of years later in the evolutionary process than the larger proteins currently known to scientists.
Representation of human cells.
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New Insights Into T-Cell Metabolism Revealed

By feeding T cells in the lab, researchers revealed a new metabolic pathway that could help make immunology more effective.
A plastic model of a kidney in a hand.
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New Method Accurately Measures Key Marker of Biological Aging

Scientists have shown that regenerative therapy to restore impaired kidney function may soon be a possibility.
A bowl of salad.
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Alternate-Day Fasting Improves Health of Patients With Fatty Liver Disease

Exercise and alternating fasting and feasting days have been shown to increase insulin sensitivity, decrease liver fat and decrease other disease markers in people with fatty liver disease.
Doctor with a stethoscope on a boy's back listening to his lungs.
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Biofilm Insights Could Help To Prevent Dangerous Lung Infections

Scientists have visualized the interaction between two important proteins that are key players in Pseudomonas’s ability to make biofilms, which could offer a promising therapeutic target to help treat lung infections in cystic fibrosis patients.
Pink and orange bubbles.
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Material Found That Can Trap and Store Volatile Gases

Researchers have identified a new "Swiss cheese-like" material that can safely store volatile gases including hydrogen and nitric oxide.
Silhouettes of three people running.
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When You Exercise Might Determine the Amount of Fat You Burn

Researchers from the Karolinska Institute and the University of Copenhagen found that the timing of exercise may fine-tune fat metabolism in mice. The study is published in the Proceedings of the National Academy of Science (PNAS).
Cells stained blue, purple and red.
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Protein Key to Tumor Cell Metabolism and Immune Evasion Identified

Tumor cells can alter their metabolism, and in doing so, dampen the body's anti-cancer immune response. A research team has identified a potential target for therapies in the protein key to this metabolic shift.
A colorized scanning electron microscopic image of the mpox virus on the surface of infected VERO E6 cells.
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Mouse Model Created To Study Mpox Virulence

Scientists have developed a mouse model of mpox and used it to demonstrate clear differences in virulence among the major genetic groups of mpox virus.
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