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Oxytocin Derivative Improves Cognitive Impairment in Mice
An oxytocin derivative has been designed to be delivered intranasally, and studies in mice have shown that it can reverse amyloid beta-induced cognitive impairment.
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How Heart Failure Disrupts Mitochondria
Investigations have uncovered some molecular mechanisms behind mitochondrial dysfunction in chronic heart failure.
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UK’s Oldest Human DNA Analyzed, Revealing Two Distinct Populations
Researchers from University College London (UCL) Institute of Archaeology, the Natural History Museum and the Francis Crick Institute have sequenced the oldest human DNA obtained from the British Isles to date.
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Transcription Factor Required for Preprograming of Heart Fibroblasts Discovered
One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing transcription factor in existing cocktails for direct cardiac reprogramming of human fibroblasts.
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Genetic Study of Polynesian Population Offers Insights on High Cholesterol
Researchers have found a genetic variant that is relatively common among people of Polynesian ancestry but rare in most other populations and could improve understanding of the genetic underpinnings of high cholesterol in all people.
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Parental Exercise Impacts Offspring’s Metabolic Health in Mice
A new study in mice has found that all forms of parental exercise improve the whole-body glucose metabolism of their offspring.
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Butterfly Wing Patterns Emerge From Non-Coding DNA
Butterfly wing patterns have a basic plan to them, which is manipulated by non-coding regulatory DNA to create the diversity of wings seen in different species, according to new research.
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Synch Mealtimes With the Circadian Clock, Suggests New Mouse Study
A new study in mice has found that restricting eating to the active period of the daily circadian rhythm limits weight gain and improves metabolic health using increased heat-generating creatine metabolism in fat cells.
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Important Immune Receptor Structure Revealed
Cryo-electron microscopy has enabled researchers to elucidate the exact molecular structure of an IgM-type B-cell receptor.
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Irresistible to Mosquitos? It Might Be Your Odors
Researchers from The Rockefeller University found that fatty acids released from the skin might produce a “fragrance” that mosquitos find irresistible. Their study is published in Cell.
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