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Scientists have shown that high-fat diets can cause rapid changes in the bone marrow of mice, driving the production of inflammatory immune cells.

The control of RNA metabolism is crucial to the regulation of animal longevity, researchers from the Max Planck Institute for Biology of Ageing in Cologne have now discovered.

Researchers have transferred the RNA editing system from moss into human cells and surprisingly, the machinery still works, finding over 900 targets for editing in human transcripts.

Blocking the inhibition of two genes by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

A molecular fluorescence sensor has revealed an abnormal distribution of lipid in the brains of patients with Huntington's disease, enabling researchers to identify a potential cause of brain dysfunction in the disease.

A team from Geneva, Switzerland, shows that the disruption of lipid temporal profiles in type 2 diabetes stiffens the membrane of pancreatic endocrine cells, which could alter their function.

Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design.

"Silent mutations" to bacterial DNA that don't affect the structure of the protein produced but instead alter the mRNA intermediate could be contributing to antibiotic resistance.

Researchers have discovered that microproteins play a previously unrecognized role in forming the electron transport chain within the mitochondria, enabling them to regulate energy supply.

According to a study, bloodstream levels of endotrophin, a protein fragment, can be used to predict outcomes in patients with a common form of heart failure.