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Key to Hepatitis A Replication Discovered
Scientists have discovered how a protein and enzymes interact to allow hepatitis A virus to replicate, and then used a known drug to stop viral replication in an animal model.
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Artificial Genes Help Understand How Cells Learn Their Location in the Body
Hox genes are responsible for ensuring cells learn and remember their location in the body, and new synthetic DNA technology has enabled researchers to create artificial versions to understand how they work.
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How Did Placentas Evolve in Mammals?
In a new study, scientists use gene expression patterns, called transcriptomics, to investigate the ancient origins of the placenta.
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Evolutionary Relationships of Ancient Invertebrates Revealed
Using cutting-edge sequencing technology and powerful computational analysis, scientists have revealed that the two phyla, Kamptozoa and Bryozoa, split from mollusks and worms earlier than previous studies have suggested, and thus they indeed form a distinct group.
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Artificial Intelligence Detects New Family of Genes in Gut Bacteria
Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence.
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Towards a More Precise and Effective Use of CRISPR
A study has investigated the role of the gRNA component of the CRISPR/Cas9 protein, in the hopes of optimizing the effectiveness of the technology.
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Vibrational Spectroscopy Provides Clues About Protein Acetylation Structures in Biological Systems
Vibrational spectroscopy has been used to identify protein acetylation, providing a more accurate method to gain a clear understanding of acetylation in biological systems.
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Elevated Blood Clotting Proteins Linked to Poor Breast Cancer Outcomes
New research has identified that higher levels of a blood clotting factor are associated with poorer outcomes for breast cancer patients, suggesting that analysis of this protein could help predict clinical outcomes.
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Oxidative Damage Study Reveals Secrets of “Zombie” Cells
Sencescent or zombie cells have lost their ability to divide, but remain otherwise functional, acting as drivers of dementia, cardiovascular disease and cancer. New research has revealed how zombie cells are formed, pointing towards therapeutics that could minimize their impact on our healthy lifespan.
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Measuring Proteins in Eye Fluid Could Identify Patients Needing Lifelong Macular Degeneration Therapy
In a study of eye fluid from 38 patients, researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision or if they can be safely weaned off the treatments.
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