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Watch How RNA Switches “On” and “Off”
Researchers discovered how one part of RNA smoothly invades and displaces another part of the same RNA, enabling the structure to rapidly and dramatically change shape. Called “strand displacement,” this mechanism appears to switch genetic expression from “on” to “off.”
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Protein Folds Into Alzheimer's-Linked Structures, But With No Link to Disease
Experts at Indiana University School of Medicine have helped identify that a common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner without a connection to disease.
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Protein Deletion Prevents Macrophage “Bad Behavior”, Reducing Atherosclerosis
UConn Health researchers how deleting a protein could prevent fat-filled macrophages narrowing blood vessels and causing heart disease.
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Blood Test Predicts Sepsis Soon After Infection
In mice, a new test predicted sepsis soon after infection, well before blood clotting and organ failure, enabling early antibiotic treatment and markedly increased survival.
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Tuberculosis Induces Premature Cellular Aging
A new study found that the cells of humans and animals who have recovered from tuberculosis had prematurely aged up to 12 to 14 years.
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Powerful New Method for Generating Protein Drugs
New software can scan a target molecule then generate proteins that bind with high affinity to the target, proposing an alternative strategy to develop drugs for cancer, diabetes and beyond.
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New Pathway for Tumor Cells To Transfer Genetic Material Discovered
University of Notre Dame researchers have discovered another way tumor cells transfer genetic material to other cells in their microenvironment, causing cancer to spread.
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Viral Protein Combats the "Same" Human and Monkey Defences Differently
The viral protein Vpu, expressed by Simian immunodeficiency virus, targets tetherin in both humans and monkeys but uses different mechanisms to do so.
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Protein "Queen" Commands Cell Invasion
A master regulator protein has been identified that adjusts metabolism within immune cells to enable cell invasion.
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Why Do Some Types of Infections Persist?
The bacterial response to environmental stress could provide the answer as to why some infections persist and could reveal new drug targets.
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