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Regulator Protein’s Structure Revealed in 3D
A research team has clarified the structure of a protein complex which is an important regulator of cellular degradation processes.
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AI System Rapidly Predicts How Two Proteins Will Attach
MIT researchers created a machine-learning model that can directly predict the complex that will form when two proteins bind together. Their technique is between 80 and 500 times faster than state-of-the-art software methods, and often predicts protein structures that are closer to actual structures that have been observed experimentally.
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The First Next-Generation COVID-19 Vaccine Combines Three Technologies
Scientists at The Wistar Institute have developed a more targeted COVID-19 vaccine that, in animal studies, shows stronger, broader, and more durable protection in a single, low dose.
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Capsule for Oral mRNA Delivery Developed and Tested
Renowned scientists and engineers from the Massachusetts Institute of Technology (MIT) have developed and tested a capsule-based system for oral delivery of mRNA therapeutics.
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Moderna Launches HIV mRNA Vaccine Clinical Trial
A phase one clinical trial testing an mRNA vaccine designed to induce B-cell immune responses in HIV patients has begun.
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New COVID-19 Mouse Model Developed To Advance Research
Researchers have altered the SARS-CoV-2 spike protein to enable replication and infection in mice, demonstrating that the ACE2 receptor is key for virus entry into host cells.
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Artificial Muscles Move in Response to Temperature and pH Changes
Scientists from the University of Freiburg’s livMatS Cluster of Excellence have succeeded in developing a muscle solely on the basis of natural proteins.
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New Approach Accelerates Cancer Biomarker Detection
Researchers have developed an approach that accelerates the detection of cancer biomarkers in samples taken at the time and place of patient care.
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The Potential of Structural Proteomics for Treating Neurodegenerative Diseases
Structural proteomics can resolve the detailed structure of protein interactions and therefore may progress understanding of neurodegenerative disease treatments.
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RNA-Based Molecule Helps Cells “Skip Over” Cystic Fibrosis Mutation
Researchers have discovered a way to modify the message containing the instruction for CFTR, forcing the protein-making machinery to skip over this “stop sign” mutation, which allows a functional version of the protein to be made.
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