Breast Cancer Protein May Predict Sensitivity to Chemotherapy
Alterations in the ratio of p53 isoforms could provide a biomarker to indicate whether breast cancer will respond to DNA-damaging therapies.
RNA-Targeting Strategy for Treating Genetic Causes of Dementia
A small molecule has been designed that can pass through the blood–brain barrier and bind to disease-causing RNA, which causes it to be degraded. Researchers propose it could be used to treat ALS and genetic causes of dementia.
Quick-Closing Valve Allows Fish To Regulate the Water in Cells
A unique, quick-closing valve in an aquaporin – a water-regulating channel protein – has been identified in a species of fish, enabling it to rapidly adapt to new environments.
Study Shows How Liver Cancer Cells Go Astray
New research from the University of Basel has unpicked the metabolic changes that convert a healthy liver cell to a tumor cell, identifying a cancer "signature" that could be used as a biomarker.
Honey Improves Key Measures of Cardiometabolic Health
A review of clinical trials on honey has revealed that it lowered fasting blood glucose, "bad" cholesterol and triglycerides, improving cardiometabolic health.
Genetic Links Between Traits Often Overstated?
Many estimates of how strongly traits and diseases share genetic signals may be inflated, according to a new UCLA-led study that indicates current methods for assessing genetic relationships between traits fail to account for mating patterns.
Genotype Affects Metabolism of Essential Fatty Acids
Genetic background has an effect on the metabolism of the essential polyunsaturated fatty acids alpha-linolenic acid and linoleic acid, a recent study from the University of Eastern Finland shows.
FDA Gives “Green Light” to Cultivated Meat Product for the First Time
On November 16, the US Food and Drug Administration (FDA) announced its first pre-market consultation for a human food made from cultured animal cells was complete. The consultation was with the California-based company UPSIDE Foods, which describes itself as the world’s first cultivated meat company, founded in 2015.
Mitochondria Have a Waste Disposal Mechanism To Get Rid of Mutated mtDNA
Scientists at the University of Cologne have discovered how cells can eliminate mutated mitochondrial DNA (mtDNA).
Antibiotic-Resistant Microbes in the Gut Make C. difficile More Infectious
Researchers have revealed that the antibiotic-resistant pathogen Enterococcus works together with
to reshape the metabolic environment in the gut and enable to thrive.