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Tuning the Immune System May Enhance Vaccines
Immunologists have identified a biological pathway that selectively controls how T follicular helper cells mature into functional components of the immune system.
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New Synthetic Circuits Rely on Protein Interactions, Not Transcription and Translation
MIT synthetic biologists have now developed an alternative approach to designing synthetic circuits, which relies exclusively on fast, reversible protein-protein interactions. This means that there's no waiting for genes to be transcribed or translated into proteins, so circuits can be turned on much faster, within seconds.
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Slowing Down Huntington’s Disease With Gene Therapy
In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington’s disease, a neurodegenerative disorder that attacks brain cells.
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Plant-Based Meat Alternatives Not Nutritionally Equivalent to Meat
Plant-based meat substitutes taste and chew remarkably similar to real beef, and the 13 items listed on their nutrition labels – vitamins, fats and protein – make them seem essentially equivalent. But deeper examination of the nutritional content of plant-based meat alternatives using metabolomics shows they’re as different as plants and animals.
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Lipids in the Blood Linked to Drug Resistance in Schizophrenia
Researchers have found lipids in the plasma of people with schizophrenia, associated with lower symptom improvement over time during treatment.
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Genetic Mechanism Behind Rett Syndrome Identified
Researchers have revealed a possible genetic pathway behind the neurological dysfunction of Rett syndrome. Deficiencies in key genes trigger neural stem cells to generate less neurons by producing more astrocytes.
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Epigenetic Landscape Reveals Glioblastoma’s Influence
The epigenetic modifications in tumor-infiltrating CD4 T-cells influenced by Glioblastoma (GBM) may be responsible for the immunosuppressed state seen in GBM patients.
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Pigments Play a Role in Tasty Tomatoes
The flavor of a tomato is an interaction between its taste and aroma. Now, researchers have revealed that the pigments that determine the colors of tomatoes also affect their flavor.
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Cellular Model of a Developing Mouse Is Built With Spatial Resolution
A new technique called sci-Space could help construct mammal embryonic development atlases that map gene expression over time and location at single-cell resolution.
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Researchers Explore Protein “Big Bang” for Advances in Medicine and Bioengineering
A new study has mapped the evolutionary history and interrelationships of protein domains over 3.8 billion years.
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