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The Origin of the Reproductive Organs
Early in human development, a fetus may have chromosomes that indicate its sex. Yet at this stage, the bipotential gonad that ultimately develops into either ovaries or testes has yet to commit to its final destiny. In a new study, researchers have laid out the development of this key facet of sexual determination in two mammalian models.
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Membrane Lipid-Producing Archaeal Enzyme Is Promiscuous
Cardolipins are a separate class of phospholipids present in the cell membranes of organisms from all domains of life. In studying the enzyme that is responsible for producing cardiolipins in archaea biochemists discovered a single archaeal enzyme can produce a range of natural and non-natural cardiolipins, as well as other phospholipids.
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Protein “Signature” of Severe COVID-19 Cases Identified
Researchers at Harvard-affiliated Massachusetts General Hospital (MGH) have identified the protein “signature” of severe COVID-19, which they describe in a new study published in Cell Reports Medicine.
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Novel Non-Coding RNAs Regulate Blood Vessel Formation
Researchers have discovered non-coding RNAs involved in regulating the gene expression of vascular endothelial growth factors, the master regulators of angiogenesis.
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Like Sea Turtles, Sharks Use the Earth’s Magnetic Fields To Navigate
A new study published in Current Biology suggests that sharks, much like sea turtles, sense the Earth’s magnetic field to navigate around the ocean.
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Enzyme That Is Critical for Kidney Health Could Help 700 Million People Worldwide
University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide.
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A Personalized Treatment Approach To Tackle Drug Resistance in Leukemia Patients
Researchers have identified a combination treatment that could potentially benefit T-ALL patients that do not respond to standard chemotherapy.
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Chemical “Nose” Sniffs Out the Smallest of Changes in DNA Structure
Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect -- until now.
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Natural Immunity to Malaria Offers Direction for Future Therapies
Researchers have identified how natural human antibodies can block malaria parasites from entering red blood cells, potentially indicating how new protective therapies could be developed against this globally significant disease.
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New COVID-19 Lung Cell Atlas Reveals Why SARS-CoV-2 Is Different
A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases.
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