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The team discovered that the modern human genome undergoes mutation which makes the adenylosuccinate lyase enzyme less stable, leading to a decrease in purine synthesis. This mutation did not occur in Neanderthals, so the scientists believe that it affected metabolism in brain tissues and thereby strongly contributed to modern humans evolving into a separate species.

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found.

Researchers at Lund University in Sweden have developed an algorithm that combines data from a simple blood test and brief memory tests, to predict with great accuracy who will develop Alzheimer's disease in the future.

Scientists have used structural biology techniques to map how important classes of neutralizing antibodies bind to the original strain of SARS-CoV-2, and how the process is disrupted by mutations found in new variants.

Scientists have found the gene expression signatures underlying the engulfing of deposits of the amyloid-beta (Aβ) protein in the brain.

A new study suggests that urine IL-1α, IL-1ra and IL-8 could be useful indicators of bladder cancer.

A research team has demonstrated that a novel precise gene-editing approach, using base editors, can reduce high LDL cholesterol levels substantially and sustainably.

A study has shown that a higher genetic risk combined with a lower BMI is associated with a higher likelihood for progression to Alzheimer's disease.

Researchers report that Caps2 mutations in mice limit the release of oxytocin, causing diminished sociality in these animals.

New research shows that people with type 1 diabetes may have features of premature heart disease induced by the condition.