News

Brazilian researchers have managed to decipher the structure of a protein found in parasites that cause neglected tropical diseases, paving the way to the development of novel medications. Thanks to the discovery it will be possible to seek more potent molecules capable of destroying the pathogens directly, with fewer adverse side-effects for patients.

Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus "package up" their genetic code, allowing them to infect cells.

Researchers show that one particular enzymatic modification of the protein tubulin, called glycylation, is essential to keep sperm swimming in a straight line. These findings imply that a perturbation of this modification could underlie some forms of male infertility in humans.

The ability to edit the genetic code of a human being in vivo may have once seemed a far-off fantasy. But the advent of CRISPR-Cas9 gene-editing technology has made it very much a reality. If athletes attempt to edit their DNA to enhance performance, how will we be able to detect it? A new study proposes a suitable method.

Proteogenomic analysis may offer new insight into matching cancer patients with an effective therapy for their particular cancer. A new study identifies three molecular subtypes in head and neck squamous cell carcinoma (HNSCC) that could be used to better determine appropriate treatment.

A protein that wreaks havoc in the nerves and heart when it clumps together can prevent the formation of toxic protein clumps associated with Alzheimer’s disease, a new study led by a UT Southwestern researcher shows. The findings could lead to new treatments for this brain-ravaging condition, which currently has no truly effective therapies and no cure.

Until now, the reason why the drug levodopa (L-Dopa), which reduces the motor symptoms of Parkinson’s disease, declines in efficacy after a few years’ use has been unknown. A side effect that then often occur is involuntary movements. A Swedish–French collaboration, led from Uppsala University, has now been able to connect the problems with defective metabolism of L-Dopa in the brain.

Researchers have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in thread and neck cancers while proposing potential new treatment strategies.

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer's disease in people who were clinically diagnosed as not having Alzheimer's disease but who perceived themselves as cognitively impaired.

A new study in Nature Medicine finds that, among over 52,000 participants, individuals who had detectable brown fat were less likely than their peers to suffer cardiac and metabolic conditions ranging from Type II diabetes to coronary artery disease, which is the leading cause of death in the United States.