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Oxford's COVID-19 Vaccine Has 70% Efficacy Rate
There are now over 170 teams of researchers working to develop a vaccine for protection against COVID-19. Over the last few weeks, a number of groups shared interim analysis data on candidates that have reached Phase III clinical testing. The latest addition is the University of Oxford – in collaboration with the pharmaceutical company AstraZeneca – who today announce an efficacy of 70.4% for the candidate, ChAdOx1 nCoV-2019.
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ChIP-Seq May Have Been Quantitative All Along
ChIP-seq provides invaluable insights into the underpinnings of health and disease, it also faces a frustrating challenge, but its results are often viewed as qualitative rather than quantitative, making interpretation difficult. A recent report suggests that ChIP-seq may have been quantitative all along.
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Coronavirus Proteins Move, Change Shape and Vibrate To Get in Our Cells
Researchers have found a strong direct relationship between the rate and intensity of the spikes' vibrations and how readily the virus could penetrate the cell.
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How a Brain Protein Helps Pancreatic Cancer Cells Survive
A recent discovery has lead to promising potential treatments for pancreatic cancer.
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A Highly Scalable Method To Monitor Protein Levels and Localizations
Researchers at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have now developed a highly scalable method which allows for the study of hundreds of proteins in parallel in order to monitor the changes of their levels and localization in the cell.
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A Comprehensive Look at the Metabolic Impact of Exercise
Short bursts of physical exercise induce changes in the body’s levels of metabolites that correlate to, and may help gauge, an individual’s cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital (MGH) has found.
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CRISPR Gene-Editing System Destroys Cancer Cells in Animal Model
Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer. The researchers developed a novel lipid nanoparticle-based delivery system that specifically targets cancer cells and destroys them by genetic manipulation.
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How Can We Block the Road to Dementia?
Researchers show that the chain reaction of Alzheimer's starts much earlier in mice than commonly assumed.
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Enzyme's Role in Scleroderma Explored in New Study
A team of MUSC researchers has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma.
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Study Explores Potential of Hepatitis C Drugs To Treat COVID-19
Researchers at the Department of Energy's Oak Ridge National Laboratory have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease.
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