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Metabolomics Meets Genomics To Improve Patient Diagnosis

Researchers from Baylor College of Medicine have integrated whole-exome sequencing and targeted metabolomics to analyze the data of a group of 170 patients. They were pleased to find that the metabolomics data informed 44 percent of the cases.
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Women’s Egg Quality Dependent on Metabolic Factors

Increasing the levels of a chemical found in all human cells could boost a woman's fertility and help select the best eggs for IVF, according to University of Queensland research.
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Common Genetic Variant Identified As Frequent Cause of Deafness

A common inherited genetic variant is a frequent cause of deafness in adults, meaning that many thousands of people are potentially at risk, reveals research.
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Milk Lipids Have Co-evolved With Mammal Species' Needs

The findings of a new study indicate a co-evolution of milk lipid composition and the specific needs of the developing organism.
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Compounds Target Key Enzyme Halting SARS-CoV-2 Replication

Researchers have identified several existing compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory.
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How Uromodulin Helps Against Urinary Tract Infections

The exact process by which uromodulin prevents inflammation had never been understood. Now an interdisciplinary team, drawn from three research groups at ETH Zurich together with researchers from the University of Zurich and the Children's Hospital Zurich, has filled this knowledge gap.
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Algae Are Promising "Green" Biocatalysts

Researchers have made a discovery that could lead to more environmental protection in the chemical industry.
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Safer and More Efficient Method To Deliver Gene Therapy

Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination.
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How Parkinson's Protein Destroys Cell Membranes

A newly developed method has revealed how the composition of cell membranes seems to be a decisive factor for how small quantities of α-synuclein cause damage.
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Battle of the Crystals

Scientists researched the process of crystallization in which competing structural forms coexist. By compensating for fluctuations, they were able to more accurately describe the process that determines the final crystalline form. This work may help industrial chemists design new methods.
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