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Proteins inside a dustbin.
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A New Way To Induce Breakdown of Pathogenic Proteins

Most diseases are caused by proteins that have spun out of control. Unfortunately, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great promise in pharmaceutical research.
Double helix structure of DNA.
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Where Do Genes Come From?

The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions around the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes.
Double helix structure of DNA.
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Gene Mutations That Promote Reproduction Tend To Shorten Lifespan

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence.
A mosquito.
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How Zika Virus Does So Much With So Little

Researchers at Sanford Burnham Prebys have shown how the virus Zika does so much with so little and may have identified a therapeutic vulnerability.
A man performs a bicep curl
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Meat Meals Help Build Muscle Faster Than Vegan Meals With Same Amount of Protein

Our muscles are constantly breaking down and building up. For that muscle building, we need protein from food. According to research, a meal with meat ensures faster muscle building than a vegan meal with the same amount of protein.
A scientist holding up a vial.
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Scientists Find a Method To Predict Which of Our Organs Will Fail First

A new study led by Stanford Medicine scientists demonstrates a simple way of studying organ aging by analyzing distinct proteins, or sets of them, in blood, enabling the prediction of individuals’ risk for diseases.
Plastic models of the brain and kidney.
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Simple Way To Measure Organ Aging Developed

A test that analyzes specific sets of proteins in the blood can tell us how fast each of our organs is aging, enabling the prediction of disease risk and earlier intervention.
A limb showing gene expression patterns.
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First Spatial Map of Human Limb Development Reveals Unexpected Insights

Scientists reveal unprecedented insights into human limb development, including the many intricate processes that govern their formation.
An elderly woman sitting in a wheelchair.
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TAF15 Protein Found in the Brains of Early-Onset Dementia Patients

Scientists have identified abnormal aggregates of a protein called TAF15 in the brains of individuals with early-onset dementia, known as frontotemporal dementia, where the cause was not previously known.
A 3D printed stencil of DECTIN-1's structure.
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Fungus-Fighting Protein Also Exacerbates Autoimmune Diseases

A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases.
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