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First Structures of α-synuclein Filaments From Human Brain
Researchers have revealed the first structures of α-synuclein filaments from human brain, which may benefit diagnosis and treatment of neurodegenerative synucleinopathies.
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Atomic “Blueprint” of Molecular Machine Involved in Membrane Protein Installation
Van Andel Institute scientists have revealed the first known atomic structure of a "molecular machine" responsible for installing critical signaling proteins into cellular membranes.
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Proteins in the Blood of COVID-19 Patients Could Help To Predict How Ill They Will Become
Researchers have found 27 potential biomarkers that are present in different levels in patients with COVID-19, depending on the severity of their symptoms. The markers could help doctors to predict how ill a patient will become and provide scientists with new targets for drug development.
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Protein Injection Shows Potential To Reverse Fragile X Symptoms in Mice
Researchers have discovered a way to replace a missing protein in the brain of mice modeling Fragile X syndrome.
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Scouring Microbial Metabolic Pathways in the Pursuit of New Therapeutics
In a new study, researchers at the Centre for Genomic Regulation (CRG), in Barcelona, describe a new method for determining active metabolic pathways in microbes using cutting-edge techniques from genomics and proteomics.
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How SARS-CoV-2 Could Be Prevented From Invading a Host Cell
Researchers have suggested that the inhibition of two key proteases on the surface of host cells could prevent SARS-CoV-2 from being able to invade.
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Mass Spectrometrists Around the World Pull Together To Share COVID-19 Data
A new coalition of more than 500 scientists from around the world has been created to share data on COVID-19 gleaned from the use of mass spectrometry techniques which examine people’s blood and other biomarkers.
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Mapping Cholesterol Metabolism in the Brain
A team of researchers led by Swansea University have developed new technology to monitor cholesterol in brain tissue which could uncover its relation to neurodegenerative disease and pave the way for the development of new treatments.
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Analyzing Blood Metabolites in ALS Could Reveal or Rule Out Biomarkers for Disease
High-throughput analysis of blood plasma could aid in the identification of diagnostic and prognostic biomarkers for ALS, according to a new study.
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Nitrogen – An Exception in the Periodic Table?
Under high pressures lighter elements have similar structures to heavier elements in the same group, except for nitrogen. However, high-pressure research has disproved this special status.
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