APOE4 Risk Gene Undermines Neuronal Insulation Process
Researchers have described how the APOE4 gene causes brain cells to mismanage cholesterol, resulting in myelin deficiency, which could be a contributing factor in Alzheimer's disease development.
Enzymes Could Encourage DNA To Spontaneously Mutate
Scientists found that the part of the process by which DNA replicates itself happens at speeds 100 times faster than previously predicted. This finding sheds new light on the assumed theory that suggests quantum effects would not survive long enough to be impacted by the replication process.
Study Is First To Use Post-Mortem Human Brain Tissue To Investigate ADHD
Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).
Lipids Influence the Formation of Protein Clumps in Parkinson’s
For the first time, researchers have shown how lipids influence the arrangement of the synuclein proteins within fibrils, which could damage nerve cells in neurodegenerative disease.
28 Million-Year-Old Gene Protects Today’s Plants Against Caterpillars
The defence mechanisms plants use to recognise and respond to a common pest – the caterpillar – has arisen from a single gene that evolved over millions of years, according to a report.
Cellular Signature Discovered That Can Detect Pediatric Sleep Apnea
Researchers have discovered how obstructive sleep apnea changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.
Measuring Levels of Three Proteins in the Blood Can Aid Detection of Undiagnosed Prediabetes
Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes.
Why Older People Are More Susceptible to the Flu
Researchers have identified that increased levels of an immune modulator in the lungs as we age contributes to the loss of macrophages that protect us from the flu, making older people more susceptible.
Gut Microbiome Plays a Key Role in Shaping Our Metabolome
According to research, the gut microbiome is largely responsible for the variation in circulating blood metabolites across people.
Susceptibility to HIV Infection May Be Impacted by Gut Bacteria
New research suggests certain gut bacteria – including one that is essential for a healthy gut microbiome – differ between people who go on to acquire HIV infection compared to those who have not become infected.