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30 Year Study Highlights Need for Therapies in Maple Syrup Urine Disease
A new study analyzing the data of Maple Syrup Urine Disease patients suggests there is a critical unmet need for safer and more effective disease-modifying interventions, including gene replacement or editing therapies.
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Missing Link in Fight-or-flight Response Identified
Researchers have uncovered how adrenaline regulates a key class of membrane proteins that are responsible for initiating the contraction of heart cells in the fight-or-flight response.
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A New Component of Blood Is Revealed
Scientists have revolutionized knowledge of the mitochondria organelle by revealing that whole functioning extracellular mitochondria are in fact found in the bloodstream.
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No Snake, No Problem – Scientists Produce Venom in a Dish
A new study published in the journal Cell outlines researchers' development of reptile organoids; specifically, organoids of the venom glands of the Cape coral snake. What's more, these organoids are capable of producing venom in vitro.
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Cellular Chaperones Could Play a Role in Alzheimer's Therapy, Suggests Mouse Study
Now, scientists at the Lewis Katz School of Medicine at Temple University show that pharmacological chaperones, molecular machines that repair or remove defective proteins, could fill a critical role in Alzheimer’s disease therapy.
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Biology Shake Up: RNA Modulates How DNA Is Transcribed
A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality.
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Biodegradable Nerve Guide Helps Regenerate Damaged Nerves
Scientists have created a biodegradable nerve guide consisting of a polymer tube filled with a growth-promoting protein, glial cell-derived neurotrophic factor, or GDNF. The results in nonhuman primate studies are promising.
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Potential Therapeutic Target for Alzheimer's
A previously unknown gene and associated protein which could potentially be suppressed to slow the advance of Alzheimer’s have been discovered, presenting a potential therapeutic target to combat the disease.
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Cell Biology: All in a Flash!
Researchers have developed a method for eliminating essential proteins from cells with a flash of light, making it possible to study the function of essential proteins.
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