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Fungi: An “Under Explored Resource” in Drug Discovery
In a new study published in Scientific Reports, scientists have combined embryology, mycology and chemistry to test secondary metabolites from >10,000 species of fungi for biological activity.
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Rewinding Metabolic Process Could Make Cancer More Susceptible to Treatment
Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments.
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Wearable Sweat Sensor Could Help Gout Patients
New research describes a mass-producible, wearable sensor that can monitor levels of metabolites and nutrients in a person's blood by analyzing their sweat.
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Evolution Promotes Novelty by Keeping Genes in Check
New research has shown how gene self-repression can reduce the potential side effects of novel gene expression so that new forms can evolve.
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Metabolic Switch for Inflammatory Diseases
A research team in Trinity College Dublin has uncovered a critical role for a protein called "PKM2" in the regulation of immune cell types at the heart of multiple inflammatory diseases.
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Key Water Purification Properties of Moringa Seeds Revealed
Researchers have used neutrons and X-rays to identify and characterize key proteins underlying the unique water purification properties of Moringa seeds. This information may allow better exploitation of this abundant resource.
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Dangers of Mother's High-fat Diet for Unborn Child
High-fat maternal diets can cause life-long changes in the brain of the unborn offspring and it is unlikely that such damage can simply be reversed by a subsequent change of diet.
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Orangutan Connected Directly to Extinct Giant Ape
Researchers have successfully reconstructed the evolutionary relationship between a two million year old giant primate and the living orangutan.
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Structure of Mitochondrial ATP Synthase Is Solved
Researchers have successfully reconstructed and solved the structure of mitochondrial ATP synthase with native lipids.
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Screening System Designed To Detect Drugs That Block Drivers of Cancer Cell Growth
A new screening system leverages redundancy in an important component of a cell – nucleotide metabolism – to help detect new drugs that specifically and potently block processes that are essential for cancer cell growth.
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