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Structure of Mitochondrial ATP Synthase Is Solved
Researchers have successfully reconstructed and solved the structure of mitochondrial ATP synthase with native lipids.
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Screening System Designed To Detect Drugs That Block Drivers of Cancer Cell Growth
A new screening system leverages redundancy in an important component of a cell – nucleotide metabolism – to help detect new drugs that specifically and potently block processes that are essential for cancer cell growth.
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Blood Test for Deadly Eye Melanoma on the Horizon?
Scientists have uncovered markers in the blood that can differentiate between a benign mole and a melanoma, while also identifying if the cancer has spread to other areas of the body.
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Unlocking Photosynthesis Could Meet Growing Food Demands
Scientists have solved the structure of a key component of photosynthesis, a discovery that could lead to photosynthesis being "redesigned" to meet urgent food security needs.
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Blood Test Could Reveal High Risk Heart Patients in Need of Treatment
Without occasionally looking under the hood, it’s difficult to predict whether expensive car repairs lie ahead. In a similar way, preventive cardiologists are looking for ways to detect early stage heart disease in people who aren’t currently in treatment.
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GlyGen Helps Researchers Answer Glycan-related Questions Using Big Data
Of the four building blocks of life – proteins, lipids, nucleic acids and glycans (carbohydrates) – the latter have received the least attention from researchers. This may be about to change as a new project, GlyGen, launches to help researchers answer glycan-related questions using big data.
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Scientists Produce a Potential Vitamin and Alzheimer’s Drug in Yeast
By engineering and optimizing baker's yeast, scientists from The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) have for the first time exploited the potential of making ergothioneine in yeast in a bio-based fashion.
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Biomarker Accurately Diagnoses Deadly Infant Disease
A diagnostic study of 136 premature infants found that a protein involved in managing harmful bacteria in the human intestine is a reliable biomarker for the noninvasive detection of necrotizing enterocolitis (NEC).
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Sugar-coating Proteins May Help Understand Brain Disease
Researchers, led by Professor Daan van Aalten in the University’s School of Life Sciences, have developed a new way to tag proteins in human cells with a small sugar molecule called O-GlcNAc. There are over 20,000 proteins in every human cell and approximately 20% of these contain O-GlcNAc.
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Puberty and Sense of Smell: What Do They Have in Common?
Researchers have identified a group of proteins that are involved in the development of the sense of smell and onset of puberty in mice, which could improve our understanding of the reproductive condition, Kallmann syndrome.
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