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New Markers for Triple Negative Breast Cancer
Two biomarkers – a 44-gene DNA Damage Response (DDIR) signature and stromal tumor-infiltrating lymphocytes (sTILs) – can serve as prognostic markers in people diagnosed with triple negative breast cancer, according to a new study.
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Researchers Develop a “FrogPhone” to Remotely Call Frogs in the Wild
Researchers have developed the 'FrogPhone', a novel device which allows scientists to call up a frog survey site and monitor them in the wild. The FrogPhone is the world's first solar-powered remote survey device that relays environmental data to the observer via text messages, whilst conducting real-time remote acoustic surveys over the phone.
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Bile Duct Biomarker? Protein May Help Predict Outcomes for Patients With Lethal Cancer
Researchers have discovered how a gene-repressing protein could help to predict survival outcomes in patients with a malignant form of bile duct cancer.
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Freeze! Scientists Snap Artificial Proteins With Atomic Precision
Scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have adapted a technique that enlists the power of electrons to visualize a soft material's atomic structure while keeping it intact.
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Blood-based "Clock" Can Tell Your Biological Age
Scientists don’t need to know how you look to guess your age. Instead, they watch a kind of physiological clock: the levels of 373 proteins circulating in your blood. If the clock is off, you may find out important things about your health.
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An "Important Piece of the Puzzle" Found by Autism Gene Study
Northwestern Medicine scientists have discovered why a specific genetic mutation causes intellectual disability and autism spectrum disorder in children.
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Worms Reveal Critical Step in Insulin Synthesis
The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes.
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Reward Circuit Protein Could Influence Addiction, Suggests Mouse Study
The reward pathway of the brain causes feelings of happiness but is also involved in behavioral disorders like schizophrenia and addiction. A breakthrough study by scientists in Japan has now identified the role of a protein called Npas4 in the reward pathway, mediated by the well-known proteins MAPK and CBP, opening doors to potential therapies for associated disorders.
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Molecular "Bodyguards" Keep Out Parkinson's
Scientists have discovered that if the dynamic binding of chaperone proteins to the Parkinson protein α-synuclein is disturbed, it can lead to cell damage and the formation of aggregates typical for the disease.
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A Genetic Network Sheds Light on the Evolution of the Modern Human Face
A study has identified a genetic network involved in the unique evolutionary trajectory of the modern human face and prosociality not found in Neanderthals.
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