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"Bone-in-a-dish" Opens Window on Cancer Initiation and Bone Regeneration
Like real bone, the material developed at OHSU has a 3D mineral structure populated with living cells, providing a unique model to study bone function, diseases, and regeneration.
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Proteins Might Restore Damaged Sound-detecting Cells in the Ear
Using genetic tools in mice, researchers at Johns Hopkins Medicine say they have identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells, are born in the mammalian inner ear.
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Novel Epigenetic Regulation Mechanism Underlies Improved Stress Response in Plants
A group of scientists has uncovered a novel epigenetic regulation mechanism, at the center of which lies a histone demethylase enzyme called lysine-specific demethylase 1-like 1 (LDL1).
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In Evolutionary Experiment, Pre-life Building Blocks Spontaneously Align
A new study has shown how fortuitously some early predecessors of protein may have fallen into line. In the laboratory, under conditions mimicking those on pre-life Earth, a small selection of amino acids linked up spontaneously into neat segments in a way that surprised researchers.
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Proteomics Approach Identifies a New Signaling Component Important for Plant Symbiosis
A proteomics-based protein-protein interaction study has led to the discovery of proteins that interact with a legume receptor that mediates signal transduction from the plasma membrane to the nucleus. This shows how symbiotic signals from symbiotic bacteria are transmitted upon perception, ultimately leading to their accommodation within the host plant.
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Experimental Respiratory Virus Vaccine Prompts Antibody Surge
A novel experimental vaccine against respiratory syncytial virus (RSV), a leading cause of severe respiratory illness in the very young and the old, has shown early promise in a Phase 1 clinical trial.
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Computational Model Reveals Prion Replication Mechanisms
A new computational model hopes to open up new research avenues to design drugs against incurable neurodegenerative disorders
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Predatory Journals Could Damage the Credibility of Scientific Publishing
'Predatory journals' pose a danger that could undermine the quality, integrity, and reliability of published scientific research, a new joint statement from three leading organizations, professional in medical writing and publication planning, has warned.
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Study Finds Higher Vitamin A Intake Linked to Lower Skin Cancer Risk
People whose diets included high levels of vitamin A had a 17 percent reduction in risk for getting the second-most-common type of skin cancer, as compared to those who ate modest amounts of foods and supplements rich in vitamin A.
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First Images of Enzyme That Drives New Class of Antibiotics
Researchers have applied knowledge about how antibiotic scaffolds are constructed in nature to help in their quest to create a new class of antibiotics. They have been able to solve the X-ray crystal structure of the enzyme that makes obafluorin, a broad spectrum antibiotic agent made by a fluorescent strain of soil bacteria.
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