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Unlocking “Fast Burning” Fat Cells May Help Weight Loss
Researchers have discovered differences in fat cells that could potentially identify people predisposed to metabolic diseases such as diabetes and cardiovascular and fatty liver disease.
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Cell's "Executioner Switch" Actions Detailed
Structural biologists have discovered how the cell switches on an executioner mechanism called "necroptosis" that induces damaged or infected cells to commit suicide to protect the body.
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Proteogenomics Holds the Key to Unlocking Cancer Therapies
Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible new therapeutic strategies.
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Personalized Cancer Therapy Trial Shows Encouraging Results
A newly published study has demonstrated the potential of using transcriptomics to help get cancer patients on treatments they're most likely to benefit from.
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Meal Timing Can Make or Break Your Cells' Circadian Rhythm
It is well known that exposure to daylight keeps our body clock in check. But what impact does meal timing have? A new study published in Cell helps answer this question and provides new insights on how cells keep a circadian rhythm. The study also has important implications for shift workers and travelers wanting to avoid jet lag.
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Unexpectedly High Proportion of Our Body's Protein Affected by Sex and Diet
Scientists from EMBL Heidelberg have discovered that the collection of proteins in an animal cell - called the proteome - is substantially affected by both the animal's sex and its diet.
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How a Shrub May Enable the “Impossible” in Treating Addiction
Scientists used a compound found in a shrub native to Africa to reveal the three major shapes of the serotonin transporter, a protein in the brain linked to anxiety and depression.
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Exposing and Exploiting Cancer’s Metabolic Addictions
Where a tumor arises dictates specific metabolic vulnerabilities, identifying potential targets for effective cancer treatments.
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The Key to a Good Night’s Sleep?
A team of researchers has now created 3D maps of MT1 and MT2 melatonin receptors revealing the structural basis of the selectivity of each receptor subtype. They intend to use this structural information to develop novel drugs capable of tackling sleep disorders.
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Cryo-EM Material Advancements May Aid Medical Research
With new substrates, researchers have the potential to get all their data on the samples in as little as an hour, as opposed to what would currently take days.
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