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Can We Stop the “Energy Engines” of Cancer?
Researchers have used the powerful tool of cryo-electron microscopy to determine the mechanism regulating the energy engines of cancer.
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Alzheimer's is a "Double-prion Disorder"
Two proteins central to the pathology of Alzheimer's disease act as prions -- misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape -- according to new UC San Francisco research.
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Brain Proteins Are a Moving Target
Surprisingly complex movements in an important neurotransmitter receptor may help explain the brain’s unpredictable response to drugs, according to a new study. New research from an international team, published this week in the journal Neuron, has revealed that the resting state of signaling proteins are much more dynamic than previously thought.
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LATE Recognized as a Disease Entity, Symptoms Similar to Alzheimer's
A recently recognized brain disorder that mimics clinical features of Alzheimer’s disease has for the first time been defined with recommended diagnostic criteria and other guidelines for advancing and catalyzing future research.
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Unlocking “Fast Burning” Fat Cells May Help Weight Loss
Researchers have discovered differences in fat cells that could potentially identify people predisposed to metabolic diseases such as diabetes and cardiovascular and fatty liver disease.
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Cell's "Executioner Switch" Actions Detailed
Structural biologists have discovered how the cell switches on an executioner mechanism called "necroptosis" that induces damaged or infected cells to commit suicide to protect the body.
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Proteogenomics Holds the Key to Unlocking Cancer Therapies
Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible new therapeutic strategies.
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Personalized Cancer Therapy Trial Shows Encouraging Results
A newly published study has demonstrated the potential of using transcriptomics to help get cancer patients on treatments they're most likely to benefit from.
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Meal Timing Can Make or Break Your Cells' Circadian Rhythm
It is well known that exposure to daylight keeps our body clock in check. But what impact does meal timing have? A new study published in Cell helps answer this question and provides new insights on how cells keep a circadian rhythm. The study also has important implications for shift workers and travelers wanting to avoid jet lag.
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Unexpectedly High Proportion of Our Body's Protein Affected by Sex and Diet
Scientists from EMBL Heidelberg have discovered that the collection of proteins in an animal cell - called the proteome - is substantially affected by both the animal's sex and its diet.
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